1JTX
Crystal structure of the multidrug binding transcriptional regulator QacR bound to crystal violet
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003700 | molecular_function | DNA-binding transcription factor activity |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 599 |
| Chain | Residue |
| A | ASN2 |
| A | ASP5 |
| A | LYS6 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 600 |
| Chain | Residue |
| B | LEU3 |
| B | ASN38 |
| B | TYR41 |
| B | LYS44 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 299 |
| Chain | Residue |
| A | LYS4 |
| A | HIS42 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 899 |
| Chain | Residue |
| D | THR24 |
| D | GLY26 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 900 |
| Chain | Residue |
| E | THR24 |
| E | THR25 |
| E | GLY26 |
| E | LYS36 |
| E | SO4249 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 900 |
| Chain | Residue |
| B | LYS66 |
| D | LEU3 |
| D | LYS4 |
| D | HIS42 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 901 |
| Chain | Residue |
| D | LEU8 |
| D | LYS12 |
| D | ILE56 |
| D | GLU57 |
| D | HOH903 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 249 |
| Chain | Residue |
| E | LYS36 |
| E | TYR40 |
| E | LYS46 |
| E | GLU47 |
| E | SO4900 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 699 |
| Chain | Residue |
| A | VAL29 |
| A | SER35 |
| A | LYS36 |
| A | GLY37 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 219 |
| Chain | Residue |
| B | HIS128 |
| B | LYS132 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 E 399 |
| Chain | Residue |
| E | LYS12 |
| E | ILE53 |
| E | ILE56 |
| E | GLU57 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 799 |
| Chain | Residue |
| A | LYS36 |
| A | TYR40 |
| E | ASN2 |
| E | ASP5 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 800 |
| Chain | Residue |
| A | TYR20 |
| A | LYS46 |
| A | GLU47 |
| A | GLU105 |
| A | TYR106 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 E 901 |
| Chain | Residue |
| E | LYS4 |
| E | HIS42 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 199 |
| Chain | Residue |
| B | GLN64 |
| B | TYR91 |
| D | GLN64 |
| D | GLU90 |
| D | TYR91 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 499 |
| Chain | Residue |
| B | LYS67 |
| D | LYS60 |
| D | GLU90 |
| D | TYR91 |
| D | HOH903 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 700 |
| Chain | Residue |
| B | THR45 |
| B | LYS46 |
| B | GLU47 |
| B | TYR106 |
| B | SO4999 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 999 |
| Chain | Residue |
| B | THR24 |
| B | THR25 |
| B | LYS46 |
| B | SO4700 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 801 |
| Chain | Residue |
| A | HIS128 |
| A | LYS132 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 802 |
| Chain | Residue |
| A | ASN2 |
| A | LEU3 |
| A | LYS4 |
| A | HIS42 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 902 |
| Chain | Residue |
| D | HIS128 |
| D | LYS132 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 239 |
| Chain | Residue |
| E | HIS128 |
| E | LYS132 |
| E | HOH912 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 779 |
| Chain | Residue |
| D | LYS17 |
| D | LYS30 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 E 649 |
| Chain | Residue |
| E | THR109 |
| E | ASN110 |
| E | SER111 |
| site_id | CC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CVI A 200 |
| Chain | Residue |
| A | THR89 |
| A | GLU90 |
| A | TYR93 |
| A | TYR103 |
| A | GLU120 |
| A | TYR123 |
| A | ILE124 |
| A | ASN154 |
| A | ASN157 |
| A | THR161 |
| B | ILE100 |
Functional Information from PROSITE/UniProt
| site_id | PS01081 |
| Number of Residues | 31 |
| Details | HTH_TETR_1 TetR-type HTH domain signature. GYnatTTgeIvklseSSkGnLYyHFkTKen.L |
| Chain | Residue | Details |
| B | GLY19-LEU49 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
