1JTK
Crystal structure of cytidine deaminase from Bacillus subtilis in complex with the inhibitor tetrahydrodeoxyuridine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004126 | molecular_function | cytidine deaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0009972 | biological_process | cytidine deamination |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| A | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004126 | molecular_function | cytidine deaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0009972 | biological_process | cytidine deamination |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| B | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| B | 1901135 | biological_process | carbohydrate derivative metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 137 |
| Chain | Residue |
| A | CYS53 |
| A | CYS86 |
| A | CYS89 |
| A | THU138 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 137 |
| Chain | Residue |
| B | CYS53 |
| B | CYS86 |
| B | CYS89 |
| B | THU1138 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THU A 138 |
| Chain | Residue |
| A | VAL26 |
| A | ASN42 |
| A | GLU44 |
| A | CYS53 |
| A | ALA54 |
| A | GLU55 |
| A | PRO85 |
| A | CYS86 |
| A | CYS89 |
| A | ZN137 |
| B | ALA46 |
| B | ALA47 |
| B | TYR48 |
| A | PHE24 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THU B 1138 |
| Chain | Residue |
| A | ALA46 |
| A | ALA47 |
| A | TYR48 |
| B | PHE24 |
| B | VAL26 |
| B | ASN42 |
| B | GLU44 |
| B | CYS53 |
| B | ALA54 |
| B | GLU55 |
| B | PRO85 |
| B | CYS86 |
| B | CYS89 |
| B | ZN137 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 41 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. CAErtALfkavsegdtefqmlavaadtpgpvs........PCga......CrqvI |
| Chain | Residue | Details |
| A | CYS53-ILE93 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | GLU55 | |
| B | GLU55 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASN42 | |
| A | CYS53 | |
| A | CYS86 | |
| A | CYS89 | |
| B | ASN42 | |
| B | CYS53 | |
| B | CYS86 | |
| B | CYS89 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| A | GLU55 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ctt |
| Chain | Residue | Details |
| B | GLU55 |
