Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004067 | molecular_function | asparaginase activity |
A | 0006520 | biological_process | amino acid metabolic process |
A | 0006528 | biological_process | asparagine metabolic process |
A | 0016787 | molecular_function | hydrolase activity |
B | 0004067 | molecular_function | asparaginase activity |
B | 0006520 | biological_process | amino acid metabolic process |
B | 0006528 | biological_process | asparagine metabolic process |
B | 0016787 | molecular_function | hydrolase activity |
C | 0004067 | molecular_function | asparaginase activity |
C | 0006520 | biological_process | amino acid metabolic process |
C | 0006528 | biological_process | asparagine metabolic process |
C | 0016787 | molecular_function | hydrolase activity |
D | 0004067 | molecular_function | asparaginase activity |
D | 0006520 | biological_process | amino acid metabolic process |
D | 0006528 | biological_process | asparagine metabolic process |
D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE DDO A 2401 |
Chain | Residue |
A | GLY14 |
A | ALA120 |
A | MET121 |
A | HOH2502 |
A | HOH2506 |
A | HOH2508 |
A | HOH2510 |
A | THR15 |
A | TYR29 |
A | ALA61 |
A | SER62 |
A | GLU63 |
A | GLY94 |
A | THR95 |
A | ASP96 |
site_id | AC2 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE DDO B 2402 |
Chain | Residue |
B | GLY14 |
B | THR15 |
B | TYR29 |
B | ALA61 |
B | SER62 |
B | GLU63 |
B | GLY94 |
B | THR95 |
B | ASP96 |
B | ALA120 |
B | MET121 |
B | HOH2403 |
B | HOH2408 |
D | HOH2604 |
site_id | AC3 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE DDO C 2403 |
Chain | Residue |
A | SER254 |
A | HOH2740 |
C | GLY14 |
C | THR15 |
C | TYR29 |
C | ALA61 |
C | SER62 |
C | GLU63 |
C | GLY94 |
C | THR95 |
C | ASP96 |
C | ALA120 |
C | MET121 |
C | HOH2605 |
C | HOH2609 |
site_id | AC4 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE DDO D 2404 |
Chain | Residue |
B | SER254 |
B | HOH2635 |
D | GLY14 |
D | THR15 |
D | TYR29 |
D | ALA61 |
D | SER62 |
D | GLU63 |
D | GLY94 |
D | THR95 |
D | ASP96 |
D | ALA120 |
D | MET121 |
D | HOH2609 |
D | HOH2613 |
D | HOH2615 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE 1PE A 2501 |
Chain | Residue |
A | GLY241 |
A | LYS243 |
A | HOH2628 |
A | HOH2690 |
C | ASP210 |
C | ARG212 |
C | THR312 |
site_id | AC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL C 2601 |
Chain | Residue |
A | ASP68 |
A | SER216 |
A | LEU217 |
A | LYS219 |
A | MET308 |
A | HOH2574 |
C | THR215 |
C | HOH2604 |
C | HOH2624 |
site_id | AC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE GOL D 2602 |
Chain | Residue |
B | LEU267 |
B | PRO291 |
B | GLY292 |
B | PRO317 |
B | HOH2444 |
B | HOH2637 |
D | ARG313 |
D | THR314 |
D | SER315 |
D | ASP316 |
D | HOH2607 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL C 2603 |
Chain | Residue |
C | ALA82 |
C | ARG83 |
C | ASP84 |
C | ASP85 |
Functional Information from PROSITE/UniProt
site_id | PS00144 |
Number of Residues | 9 |
Details | ASN_GLN_ASE_1 Asparaginase / glutaminase active site signature 1. IlATGGTIA |
Chain | Residue | Details |
A | ILE9-ALA17 | |
site_id | PS00917 |
Number of Residues | 11 |
Details | ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GvVitHGTDTV |
Chain | Residue | Details |
A | GLY88-VAL98 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | THR15 | |
B | THR15 | |
C | THR15 | |
D | THR15 | |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | BINDING: |
Chain | Residue | Details |
A | SER62 | |
A | THR95 | |
B | SER62 | |
B | THR95 | |
C | SER62 | |
C | THR95 | |
D | SER62 | |
D | THR95 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
A | THR15 | |
A | THR95 | |
A | ASP96 | |
A | TYR29 | |
A | LYS168 | |
site_id | CSA2 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
B | THR15 | |
B | THR95 | |
B | ASP96 | |
B | TYR29 | |
B | LYS168 | |
site_id | CSA3 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
C | THR15 | |
C | THR95 | |
C | ASP96 | |
C | TYR29 | |
C | LYS168 | |
site_id | CSA4 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
D | THR15 | |
D | THR95 | |
D | ASP96 | |
D | TYR29 | |
D | LYS168 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
A | VAL284 | |
C | THR15 | |
C | THR95 | |
C | TYR29 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
D | THR15 | |
D | THR95 | |
D | TYR29 | |
B | VAL284 | |
site_id | CSA7 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
A | THR15 | |
A | THR95 | |
A | TYR29 | |
C | VAL284 | |
site_id | CSA8 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 3eca |
Chain | Residue | Details |
D | VAL284 | |
B | THR15 | |
B | THR95 | |
B | TYR29 | |