Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016692 | molecular_function | NADH peroxidase activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD A 448 |
| Chain | Residue |
| A | GLY11 |
| A | GLU32 |
| A | LYS33 |
| A | CSO42 |
| A | THR77 |
| A | GLU78 |
| A | ILE79 |
| A | SER110 |
| A | PRO111 |
| A | GLY112 |
| A | ALA113 |
| A | MET131 |
| A | ARG132 |
| A | TYR159 |
| A | ILE160 |
| A | ASN247 |
| A | GLY280 |
| A | ASP281 |
| A | ALA297 |
| A | LEU298 |
| A | ALA299 |
| A | PHE424 |
| A | HOH504 |
| A | HOH661 |
| A | HOH668 |
| A | LEU6 |
| A | GLY7 |
| A | SER9 |
| A | HIS10 |
| site_id | ACT |
| Number of Residues | 5 |
| Details | CSO 42 IS THE NATIVE, ACTIVE CYSTEINE-SULFENIC ACID (SOH). |
| Chain | Residue |
| A | CSO42 |
| A | HIS10 |
| A | ARG303 |
| A | TYR159 |
| A | FAD448 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"8756456","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Redox-active","evidences":[{"source":"PubMed","id":"8756456","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8425532","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8756456","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8425532","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Cysteine sulfenic acid (-SOH)","evidences":[{"source":"PubMed","id":"8756456","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | |
| Chain | Residue | Details |
| A | HIS10 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 895 |
| Chain | Residue | Details |
| A | HIS10 | proton shuttle (general acid/base) |
| A | SER41 | electrostatic stabiliser |
| A | GLY43 | covalent catalysis, proton shuttle (general acid/base) |
| A | ARG307 | proton shuttle (general acid/base) |
