1JN0
Crystal structure of the non-regulatory A4 isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
| O | 0006006 | biological_process | glucose metabolic process |
| O | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| O | 0050661 | molecular_function | NADP binding |
| O | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 O 6336 |
| Chain | Residue |
| O | THR179 |
| O | ASP181 |
| O | ARG231 |
| O | NDP6335 |
| O | HOH6349 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 O 6337 |
| Chain | Residue |
| O | ALA210 |
| O | SER148 |
| O | THR150 |
| O | THR208 |
| O | GLY209 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1336 |
| Chain | Residue |
| A | THR179 |
| A | ASP181 |
| A | ARG231 |
| A | NDP1335 |
| A | HOH1343 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1337 |
| Chain | Residue |
| A | SER148 |
| A | THR150 |
| A | SER207 |
| A | THR208 |
| A | GLY209 |
| A | ALA210 |
| A | HOH1344 |
| A | HOH1392 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2336 |
| Chain | Residue |
| B | THR179 |
| B | ASP181 |
| B | ARG195 |
| B | ARG231 |
| B | NDP2335 |
| B | HOH2343 |
| B | HOH2376 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2337 |
| Chain | Residue |
| B | SER148 |
| B | THR150 |
| B | THR208 |
| B | GLY209 |
| B | ALA210 |
| B | HOH2355 |
| B | HOH2356 |
| site_id | AC7 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE NDP O 6335 |
| Chain | Residue |
| O | GLY9 |
| O | ARG10 |
| O | ILE11 |
| O | ASN31 |
| O | THR33 |
| O | ASP76 |
| O | ARG77 |
| O | GLY95 |
| O | THR96 |
| O | GLY97 |
| O | PHE99 |
| O | THR119 |
| O | ALA120 |
| O | SER188 |
| O | ASN313 |
| O | TYR317 |
| O | SO46336 |
| O | HOH6341 |
| O | HOH6345 |
| O | HOH6367 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NDP A 1335 |
| Chain | Residue |
| A | GLY9 |
| A | ARG10 |
| A | ILE11 |
| A | ASN31 |
| A | THR33 |
| A | ARG77 |
| A | GLY95 |
| A | THR96 |
| A | GLY97 |
| A | THR119 |
| A | ALA120 |
| A | ASN313 |
| A | TYR317 |
| A | SO41336 |
| A | HOH1358 |
| B | SER188 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NDP B 2335 |
| Chain | Residue |
| A | SER188 |
| B | ARG10 |
| B | ILE11 |
| B | ASN31 |
| B | THR33 |
| B | ASP76 |
| B | ARG77 |
| B | GLY95 |
| B | THR96 |
| B | GLY97 |
| B | PHE99 |
| B | THR119 |
| B | ALA120 |
| B | ASN313 |
| B | TYR317 |
| B | SO42336 |
| B | HOH2374 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
| Chain | Residue | Details |
| O | ALA147-LEU154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11846565","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12705826","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15236965","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17573533","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Site: {"description":"Activates thiol group during catalysis","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| O | CYS149 | |
| O | HIS176 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| A | CYS149 | |
| A | HIS176 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| B | CYS149 | |
| B | HIS176 |
