Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1JKV

Crystal Structure of Manganese Catalase from Lactobacillus plantarum complexed with azide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004096	molecular_function	catalase activity
A	0004601	molecular_function	peroxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004096	molecular_function	catalase activity
B	0004601	molecular_function	peroxidase activity
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004096	molecular_function	catalase activity
C	0004601	molecular_function	peroxidase activity
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004096	molecular_function	catalase activity
D	0004601	molecular_function	peroxidase activity
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification
E	0004096	molecular_function	catalase activity
E	0004601	molecular_function	peroxidase activity
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
E	0098869	biological_process	cellular oxidant detoxification
F	0004096	molecular_function	catalase activity
F	0004601	molecular_function	peroxidase activity
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
F	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 4272

Chain	Residue
A	ASP57
A	ASP61
F	ASN218
F	SER220
F	GLY222
F	HOH9361

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA B 5272

Chain	Residue
C	SER220
C	GLY222
C	HOH6343
B	ASP57
B	ASP61
C	ASN218

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 6272

Chain	Residue
B	ASN218
B	SER220
B	GLY222
B	HOH9400
C	ASP57
C	ASP61

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 7272

Chain	Residue
D	ASP57
D	ASP61
E	ASN218
E	SER220
E	GLY222
E	HOH8380

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA E 8272

Chain	Residue
D	ASN218
D	SER220
D	GLY222
D	HOH7389
E	ASP57
E	ASP61

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA F 9272

Chain	Residue
A	ASN218
A	SER220
A	GLY222
A	HOH5396
F	ASP57
F	ASP61

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH A 4269

Chain	Residue
A	GLU66
A	HIS69
A	HIS181
A	MN34267
A	MN34268
A	OH4270
A	OH4271
A	AZI4281

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH A 4270

Chain	Residue
A	GLU35
A	GLU66
A	ARG147
A	GLU148
A	MN34267
A	MN34268
A	OH4269
A	OH4271
A	AZI4281

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH A 4271

Chain	Residue
A	GLU35
A	HIS69
A	LEU174
A	GLU178
A	MN34267
A	OH4269
A	OH4270
A	AZI4281

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH B 5269

Chain	Residue
B	GLU66
B	HIS69
B	HIS181
B	MN35267
B	MN35268
B	OH5270
B	OH5271
B	AZI5281

site_id	BC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE OH B 5270

Chain	Residue
B	GLU35
B	GLU66
B	ARG147
B	GLU148
B	GLU178
B	MN35267
B	MN35268
B	OH5269
B	OH5271
B	AZI5281

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH B 5271

Chain	Residue
B	GLU35
B	HIS69
B	LEU174
B	GLU178
B	MN35267
B	OH5269
B	OH5270
B	AZI5281

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH C 6269

Chain	Residue
C	GLU66
C	HIS69
C	HIS181
C	MN36267
C	MN36268
C	OH6270
C	OH6271
C	AZI6281

site_id	BC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE OH C 6270

Chain	Residue
C	GLU178
C	MN36267
C	MN36268
C	OH6269
C	OH6271
C	AZI6281
C	GLU35
C	GLU66
C	ARG147
C	GLU148

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE OH C 6271

Chain	Residue
C	GLU35
C	HIS69
C	GLU178
C	MN36267
C	OH6269
C	OH6270
C	AZI6281

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH D 7269

Chain	Residue
D	GLU66
D	HIS69
D	HIS181
D	MN37267
D	MN37268
D	OH7270
D	OH7271
D	AZI7281

site_id	BC8
Number of Residues	10
Details	BINDING SITE FOR RESIDUE OH D 7270

Chain	Residue
D	GLU35
D	GLU66
D	ARG147
D	GLU148
D	GLU178
D	MN37267
D	MN37268
D	OH7269
D	OH7271
D	AZI7281

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH D 7271

Chain	Residue
D	GLU35
D	HIS69
D	LEU174
D	GLU178
D	MN37267
D	OH7269
D	OH7270
D	AZI7281

site_id	CC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH E 8269

Chain	Residue
E	GLU66
E	HIS69
E	HIS181
E	MN38267
E	MN38268
E	OH8270
E	OH8271
E	AZI8281

site_id	CC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH E 8270

Chain	Residue
E	GLU35
E	GLU66
E	ARG147
E	GLU148
E	MN38267
E	MN38268
E	OH8269
E	OH8271
E	AZI8281

site_id	CC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH E 8271

Chain	Residue
E	GLU35
E	HIS69
E	LEU174
E	GLU178
E	MN38267
E	OH8269
E	OH8270
E	AZI8281

site_id	CC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH F 9269

Chain	Residue
F	GLU66
F	HIS69
F	HIS181
F	MN39267
F	MN39268
F	OH9270
F	OH9271
F	AZI9281

site_id	CC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE OH F 9270

Chain	Residue
F	GLU35
F	GLU66
F	ARG147
F	GLU148
F	MN39267
F	MN39268
F	OH9269
F	OH9271
F	AZI9281

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE OH F 9271

Chain	Residue
F	GLU35
F	HIS69
F	LEU174
F	GLU178
F	MN39267
F	OH9269
F	OH9270
F	AZI9281

site_id	CC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE AZI A 4281

Chain	Residue
A	GLU35
A	HIS69
A	LEU174
A	GLU178
A	MN34267
A	OH4269
A	OH4270
A	OH4271
A	HOH5459

site_id	CC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE AZI B 5281

Chain	Residue
B	GLU35
B	HIS69
B	LEU174
B	GLU178
B	MN35267
B	OH5269
B	OH5270
B	OH5271
B	HOH9467

site_id	CC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AZI C 6281

Chain	Residue
C	GLU35
C	HIS69
C	LEU174
C	GLU178
C	MN36267
C	OH6269
C	OH6270
C	OH6271

site_id	DC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AZI D 7281

Chain	Residue
D	GLU35
D	HIS69
D	LEU174
D	GLU178
D	MN37267
D	OH7269
D	OH7270
D	OH7271

site_id	DC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE AZI E 8281

Chain	Residue
E	GLU35
E	HIS69
E	LEU174
E	GLU178
E	MN38267
E	OH8269
E	OH8270
E	OH8271
E	HOH8477

site_id	DC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AZI F 9281

Chain	Residue
F	GLU35
F	HIS69
F	LEU174
F	GLU178
F	MN39267
F	OH9269
F	OH9270
F	OH9271

site_id	DC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 A 4267

Chain	Residue
A	GLU35
A	GLU66
A	HIS69
A	MN34268
A	OH4269
A	OH4270
A	OH4271
A	AZI4281

site_id	DC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 A 4268

Chain	Residue
A	GLU66
A	ARG147
A	GLU148
A	HIS181
A	MN34267
A	OH4269
A	OH4270

site_id	DC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 B 5267

Chain	Residue
B	GLU35
B	GLU66
B	HIS69
B	MN35268
B	OH5269
B	OH5270
B	OH5271
B	AZI5281

site_id	DC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 B 5268

Chain	Residue
B	GLU66
B	ARG147
B	GLU148
B	HIS181
B	MN35267
B	OH5269
B	OH5270

site_id	DC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 C 6267

Chain	Residue
C	GLU35
C	GLU66
C	HIS69
C	MN36268
C	OH6269
C	OH6270
C	OH6271
C	AZI6281

site_id	DC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 C 6268

Chain	Residue
C	GLU66
C	ARG147
C	GLU148
C	HIS181
C	MN36267
C	OH6269
C	OH6270

site_id	EC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 D 7267

Chain	Residue
D	GLU35
D	GLU66
D	HIS69
D	MN37268
D	OH7269
D	OH7270
D	OH7271
D	AZI7281

site_id	EC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 D 7268

Chain	Residue
D	GLU66
D	ARG147
D	GLU148
D	HIS181
D	MN37267
D	OH7269
D	OH7270

site_id	EC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 E 8267

Chain	Residue
E	GLU35
E	GLU66
E	HIS69
E	MN38268
E	OH8269
E	OH8270
E	OH8271
E	AZI8281

site_id	EC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 E 8268

Chain	Residue
E	GLU66
E	ARG147
E	GLU148
E	HIS181
E	MN38267
E	OH8269
E	OH8270

site_id	EC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MN3 F 9267

Chain	Residue
F	GLU35
F	GLU66
F	HIS69
F	MN39268
F	OH9269
F	OH9270
F	OH9271
F	AZI9281

site_id	EC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN3 F 9268

Chain	Residue
F	GLU66
F	ARG147
F	GLU148
F	HIS181
F	MN39267
F	OH9269
F	OH9270

site_id	EC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 4283

Chain	Residue
A	SER74
A	THR75
A	GLY78
A	ASN115
A	ALA116
A	HOH5299
B	TRP47
F	ILE254

site_id	EC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 4284

Chain	Residue
A	SER74
A	SER117
A	LEU118
A	HOH5359
B	SER44
B	HOH9440

site_id	EC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO F 4285

Chain	Residue
A	VAL145
A	GLN189
A	HOH5392
F	ARG142
F	VAL145
F	GLN189

site_id	FC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO B 5283

Chain	Residue
A	TRP47
B	SER74
B	THR75
B	GLY78
B	ASN115
B	ALA116
B	HOH9297
C	ILE254

site_id	FC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 5284

Chain	Residue
A	SER44
A	HOH5319
A	HOH5426
B	SER74
B	SER117

site_id	FC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO C 6283

Chain	Residue
B	ILE254
C	SER74
C	THR75
C	GLY78
C	ASN115
C	ALA116
C	HOH6323
E	TRP47

site_id	FC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO C 6284

Chain	Residue
C	SER74
C	ALA116
C	SER117
C	LEU118
C	HOH6393
C	HOH6462
E	SER44

site_id	FC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO C 6285

Chain	Residue
B	GLN189
C	GLN189

site_id	FC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO D 7283

Chain	Residue
D	SER74
D	THR75
D	GLY78
D	ASN115
D	ALA116
D	HOH7305
F	TRP47

site_id	FC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 7284

Chain	Residue
D	SER74
D	ALA116
D	SER117
D	HOH7348
D	HOH7429
F	SER44

site_id	FC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 7285

Chain	Residue
D	ARG142
D	VAL145
D	GLN189
E	ARG142
E	GLN189
E	HOH8414

site_id	FC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO E 8283

Chain	Residue
C	TRP47
D	ILE254
E	SER74
E	THR75
E	GLY78
E	ASN115
E	ALA116
E	HOH8301

site_id	GC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO E 8284

Chain	Residue
C	SER44
C	TRP47
C	HOH6447
E	SER74
E	SER117
E	HOH8349

site_id	GC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO F 9283

Chain	Residue
A	ILE254
D	TRP47
F	SER74
F	THR75
F	GLY78
F	ASN115
F	ALA116
F	HOH9311

site_id	GC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO F 9284

Chain	Residue
D	SER44
D	HOH7432
F	SER74
F	ALA116
F	SER117
F	LEU118
F	HOH9349

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	138
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	66
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11587647","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12631270","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JKV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1O9I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
A	GLU178

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
B	GLU178

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
C	GLU178

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
D	GLU178

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
E	GLU178

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1o9i

Chain	Residue	Details
F	GLU178

site_id	MCSA1
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
A	GLU35	metal ligand
A	GLU66	metal ligand
A	HIS69	metal ligand
A	GLU148	metal ligand
A	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
A	HIS181	metal ligand

site_id	MCSA2
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
B	GLU35	metal ligand
B	GLU66	metal ligand
B	HIS69	metal ligand
B	GLU148	metal ligand
B	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
B	HIS181	metal ligand

site_id	MCSA3
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
C	GLU35	metal ligand
C	GLU66	metal ligand
C	HIS69	metal ligand
C	GLU148	metal ligand
C	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
C	HIS181	metal ligand

site_id	MCSA4
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
D	GLU35	metal ligand
D	GLU66	metal ligand
D	HIS69	metal ligand
D	GLU148	metal ligand
D	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
D	HIS181	metal ligand

site_id	MCSA5
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
E	GLU35	metal ligand
E	GLU66	metal ligand
E	HIS69	metal ligand
E	GLU148	metal ligand
E	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
E	HIS181	metal ligand

site_id	MCSA6
Number of Residues	6
Details	M-CSA 572

Chain	Residue	Details
F	GLU35	metal ligand
F	GLU66	metal ligand
F	HIS69	metal ligand
F	GLU148	metal ligand
F	GLU178	proton acceptor, proton donor, proton shuttle (general acid/base)
F	HIS181	metal ligand

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)