1JKM
BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE
Functional Information from GO Data
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | a catalytic site defined by CSA, PubMed 10201402 |
| Chain | Residue | Details |
| A | SER202 | |
| A | HIS338 | |
| A | ASP308 |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 453 |
| Chain | Residue | Details |
| A | GLY127 | electrostatic stabiliser |
| A | GLY128 | electrostatic stabiliser |
| A | SER202 | covalent catalysis, proton shuttle (general acid/base) |
| A | TYR233 | electrostatic stabiliser |
| A | TYR238 | electrostatic stabiliser |
| A | ASP308 | electrostatic stabiliser, modifies pKa |
| A | HIS338 | electrostatic stabiliser, proton shuttle (general acid/base) |
| site_id | MCSA2 |
| Number of Residues | 7 |
| Details | M-CSA 453 |
| Chain | Residue | Details |
| B | GLY127 | electrostatic stabiliser |
| B | GLY128 | electrostatic stabiliser |
| B | SER202 | covalent catalysis, proton shuttle (general acid/base) |
| B | TYR233 | electrostatic stabiliser |
| B | TYR238 | electrostatic stabiliser |
| B | ASP308 | electrostatic stabiliser, modifies pKa |
| B | HIS338 | electrostatic stabiliser, proton shuttle (general acid/base) |
