Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1JKE

D-Tyr tRNATyr deacylase from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0002161	molecular_function	aminoacyl-tRNA deacylase activity
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006399	biological_process	tRNA metabolic process
A	0009408	biological_process	response to heat
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0019478	biological_process	D-amino acid catabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0043908	molecular_function	Ser(Gly)-tRNA(Ala) hydrolase activity
A	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
A	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
A	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
A	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
B	0000049	molecular_function	tRNA binding
B	0002161	molecular_function	aminoacyl-tRNA deacylase activity
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006399	biological_process	tRNA metabolic process
B	0009408	biological_process	response to heat
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0019478	biological_process	D-amino acid catabolic process
B	0042803	molecular_function	protein homodimerization activity
B	0043908	molecular_function	Ser(Gly)-tRNA(Ala) hydrolase activity
B	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
B	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
B	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
B	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
C	0000049	molecular_function	tRNA binding
C	0002161	molecular_function	aminoacyl-tRNA deacylase activity
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006399	biological_process	tRNA metabolic process
C	0009408	biological_process	response to heat
C	0016787	molecular_function	hydrolase activity
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0019478	biological_process	D-amino acid catabolic process
C	0042803	molecular_function	protein homodimerization activity
C	0043908	molecular_function	Ser(Gly)-tRNA(Ala) hydrolase activity
C	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
C	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
C	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
C	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity
D	0000049	molecular_function	tRNA binding
D	0002161	molecular_function	aminoacyl-tRNA deacylase activity
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006399	biological_process	tRNA metabolic process
D	0009408	biological_process	response to heat
D	0016787	molecular_function	hydrolase activity
D	0016788	molecular_function	hydrolase activity, acting on ester bonds
D	0019478	biological_process	D-amino acid catabolic process
D	0042803	molecular_function	protein homodimerization activity
D	0043908	molecular_function	Ser(Gly)-tRNA(Ala) hydrolase activity
D	0051499	molecular_function	D-aminoacyl-tRNA deacylase activity
D	0051500	molecular_function	D-tyrosyl-tRNA(Tyr) deacylase activity
D	0106026	molecular_function	Gly-tRNA(Ala) deacylase activity
D	0106074	biological_process	aminoacyl-tRNA metabolism involved in translational fidelity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 901

Chain	Residue
B	ASP107
B	GLU111
C	ASP100
D	GLU18

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 902

Chain	Residue
B	GLU18
D	GLU103
D	ASP107
D	HOH1087
D	HOH1088

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 903

Chain	Residue
B	GLU22
B	HOH1020
B	HOH1021
D	GLU111
D	HOH1270

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN D 904

Chain	Residue
D	ASP100
D	ASP100
D	HOH1103
D	HOH1103
D	HOH1376
D	HOH1376

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 905

Chain	Residue
A	GLU18
A	HOH1134
C	GLU103
C	ASP107

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 906

Chain	Residue
A	GLU16
A	HOH1325
B	GLU47

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 907

Chain	Residue
B	ASP128
D	ASP36
D	HOH1184
D	HOH1189

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 908

Chain	Residue
A	GLU111
A	HOH1234
C	GLU22
C	HOH1230
C	HOH1350
C	HOH1353

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 909

Chain	Residue
A	GLU103
A	ASP107
C	GLU18
C	HOH1404
C	HOH1416

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 910

Chain	Residue
C	GLU117
C	HOH1308
C	HOH1316
C	HOH1414
C	HOH1415

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ZN C 911

Chain	Residue
C	LYS41
C	HOH1044
C	HOH1105
C	HOH1118
C	HOH1288
C	HOH1378
C	HOH1380

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN B 912

Chain	Residue
B	HOH1254
B	HOH1370
B	HOH1413
B	HOH1417
B	HOH1418
B	HOH1419

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Motif: {"description":"Gly-cisPro motif, important for rejection of L-amino acids","evidences":[{"source":"HAMAP-Rule","id":"MF_00518","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24302572","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)