1JJU

Structure of a Quinohemoprotein Amine Dehydrogenase with a Unique Redox Cofactor and Highly Unusual Crosslinking

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009055	molecular_function	electron transfer activity
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
C	0016491	molecular_function	oxidoreductase activity
C	0016638	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors
C	0042597	cellular_component	periplasmic space

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 996

Chain	Residue
B	PHE244
B	HOH1167
C	ASP12
C	ASP33
C	TRQ43
C	TBU993

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site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM A 991

Chain	Residue
A	HIS15
A	ARG25
A	ILE26
A	THR39
A	ARG42
A	MET43
A	HIS47
A	VAL49
A	ARG114
A	PHE125
A	HEM992
A	HOH1139
A	HOH1267
B	LEU107
B	THR108
B	HIS109
A	ALA10
A	CYS11
A	CYS14

---

site_id	AC3
Number of Residues	24
Details	BINDING SITE FOR RESIDUE HEM A 992

Chain	Residue
A	LYS31
A	THR39
A	ARG42
A	ARG45
A	THR99
A	CYS100
A	ARG102
A	CYS103
A	HIS104
A	ARG108
A	VAL109
A	GLN112
A	ARG114
A	LEU122
A	HIS126
A	PHE130
A	GLN136
A	LEU156
A	HEM991
A	HOH996
A	HOH1001
A	HOH1007
A	HOH1008
A	HOH1059

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TBU C 993

Chain	Residue
B	PHE244
C	ASP12
C	GLY36
C	TRP42
C	TRQ43
C	NA996

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE TBU B 994

Chain	Residue
B	GLU132

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TBU A 995

Chain	Residue
A	ASP257
A	ILE263
A	HOH1119
B	ARG128

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:12925784, ECO:0000305|PubMed:11717396

Chain	Residue	Details
C	ASP33

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Tryptophylquinone => ECO:0000269|PubMed:11717396, ECO:0000269|PubMed:12925784

Chain	Residue	Details
C	TRQ43

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: 4-cysteinyl-glutamic acid (Cys-Glu) => ECO:0000269|PubMed:11717396

Chain	Residue	Details
C	CYS7
C	GLU16

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	CROSSLNK: 3-cysteinyl-aspartic acid (Cys-Asp) => ECO:0000269|PubMed:11717396

Chain	Residue	Details
C	CYS27
C	ASP33
C	CYS41
C	ASP49

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	CROSSLNK: 4'-cysteinyl-tryptophylquinone (Cys-Trp) => ECO:0000269|PubMed:11717396, ECO:0000269|PubMed:12925784

Chain	Residue	Details
C	CYS37
C	TRQ43

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