1JHN

Crystal Structure of the Lumenal Domain of Calnexin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005783	cellular_component	endoplasmic reticulum
A	0006457	biological_process	protein folding
A	0051082	molecular_function	unfolded protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 900

Chain	Residue
A	SER75
A	ASP118
A	LYS119
A	ASP437

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Functional Information from PROSITE/UniProt

site_id	PS00803
Number of Residues	16
Details	CALRETICULIN_1 Calreticulin family signature 1. NfQNgieCGGAYVKLL

Chain	Residue	Details
A	ASN154-LEU169

---

site_id	PS00804
Number of Residues	9
Details	CALRETICULIN_2 Calreticulin family signature 2. IMFGPDkCG

Chain	Residue	Details
A	ILE188-GLY196

---

site_id	PS00805
Number of Residues	13
Details	CALRETICULIN_REPEAT Calreticulin family repeated motif signature. IeDpEdqKPEDWD

Chain	Residue	Details
A	ILE277-ASP289
A	ILE294-ASN306
A	VAL332-ASP344

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Repeat: {"description":"1-1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	11
Details	Repeat: {"description":"1-2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	11
Details	Repeat: {"description":"1-3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	11
Details	Repeat: {"description":"1-4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	10
Details	Repeat: {"description":"2-1"}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	10
Details	Repeat: {"description":"2-2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	10
Details	Repeat: {"description":"2-3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	10
Details	Repeat: {"description":"2-4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	133
Details	Region: {"description":"P domain (Extended arm)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	123
Details	Region: {"description":"4 X approximate repeats"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	33
Details	Region: {"description":"Interaction with PPIB","evidences":[{"source":"PubMed","id":"20801878","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	38
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	22
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11583625","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11583625","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P14211","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P27824","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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