Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0001217 | molecular_function | DNA-binding transcription repressor activity |
| A | 0002057 | molecular_function | guanine binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 1900372 | biological_process | negative regulation of purine nucleotide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 799 |
| Chain | Residue |
| A | HIS291 |
| A | GLN292 |
| A | PRO293 |
| A | LYS294 |
| A | ASP295 |
| A | SER296 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 800 |
| Chain | Residue |
| A | HOH880 |
| A | ARG52 |
| A | HIS58 |
| A | LYS60 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE HPA A 599 |
| Chain | Residue |
| A | TYR73 |
| A | PHE74 |
| A | ARG190 |
| A | THR192 |
| A | ARG196 |
| A | PHE221 |
| A | ASP275 |
| A | HOH808 |
| A | HOH832 |
Functional Information from PROSITE/UniProt
| site_id | PS00356 |
| Number of Residues | 19 |
| Details | HTH_LACI_1 LacI-type HTH domain signature. IkDVAkrAnVSttTVshVI |
| Chain | Residue | Details |
| A | ILE4-ILE22 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | DNA_BIND: H-T-H motif |
| Chain | Residue | Details |
| A | LYS5-LYS24 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | DNA_BIND: |
| Chain | Residue | Details |
| A | ALA49-ASN57 | |
| Chain | Residue | Details |
| A | PHE74 | |
| A | ASN191 | |
| A | GLY193 | |
| A | GLU222 | |
| A | ASN276 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Is the key determinant of 6-oxopurine corepressor specificity |
| Chain | Residue | Details |
| A | ASN191 | |
