1JG8
Crystal Structure of Threonine Aldolase (Low-specificity)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006545 | biological_process | glycine biosynthetic process |
| A | 0006567 | biological_process | threonine catabolic process |
| A | 0008732 | molecular_function | L-allo-threonine aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006545 | biological_process | glycine biosynthetic process |
| B | 0006567 | biological_process | threonine catabolic process |
| B | 0008732 | molecular_function | L-allo-threonine aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006545 | biological_process | glycine biosynthetic process |
| C | 0006567 | biological_process | threonine catabolic process |
| C | 0008732 | molecular_function | L-allo-threonine aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006545 | biological_process | glycine biosynthetic process |
| D | 0006567 | biological_process | threonine catabolic process |
| D | 0008732 | molecular_function | L-allo-threonine aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 901 |
| Chain | Residue |
| B | THR12 |
| B | THR14 |
| B | SER202 |
| B | ALA207 |
| C | GLN236 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 902 |
| Chain | Residue |
| D | GLN236 |
| A | THR12 |
| A | THR14 |
| A | SER202 |
| A | ALA207 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA D 903 |
| Chain | Residue |
| A | GLN236 |
| D | THR12 |
| D | THR14 |
| D | SER202 |
| D | ALA207 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 904 |
| Chain | Residue |
| B | GLN236 |
| C | THR12 |
| C | THR14 |
| C | SER202 |
| C | ALA207 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 905 |
| Chain | Residue |
| A | ASP326 |
| B | ASN330 |
| B | GLU333 |
| B | HOH992 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 906 |
| Chain | Residue |
| A | ASN292 |
| A | SER347 |
| A | HOH936 |
| D | ASN330 |
| D | GLU333 |
| D | HOH970 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 907 |
| Chain | Residue |
| A | GLN75 |
| A | ARG76 |
| A | HOH1005 |
| B | GLN75 |
| B | ARG76 |
| B | HOH1045 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C 908 |
| Chain | Residue |
| C | GLN75 |
| C | ARG76 |
| C | HOH981 |
| D | GLN75 |
| D | ARG76 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | TYR34 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | ASP172 | |
| B | HIS87 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | ASP172 | |
| C | HIS87 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | ASP172 | |
| D | HIS87 |
| site_id | CSA13 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | ASP172 | |
| A | HIS87 | |
| A | GLU139 |
| site_id | CSA14 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | ASP172 | |
| B | HIS87 | |
| B | GLU139 |
| site_id | CSA15 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | ASP172 | |
| C | HIS87 | |
| C | GLU139 |
| site_id | CSA16 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | ASP172 | |
| D | HIS87 | |
| D | GLU139 |
| site_id | CSA17 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | ASP172 | |
| A | PHE89 |
| site_id | CSA18 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | ASP172 | |
| B | PHE89 |
| site_id | CSA19 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | ASP172 | |
| C | PHE89 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | TYR34 |
| site_id | CSA20 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | ASP172 | |
| D | PHE89 |
| site_id | CSA21 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | GLU36 |
| site_id | CSA22 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | GLU36 |
| site_id | CSA23 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | GLU36 |
| site_id | CSA24 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | GLU36 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | TYR34 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | TYR34 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | TRP90 | |
| A | ASP172 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| B | TRP90 | |
| B | ASP172 |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| C | TRP90 | |
| C | ASP172 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| D | TRP90 | |
| D | ASP172 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ax4 |
| Chain | Residue | Details |
| A | ASP172 | |
| A | HIS87 |
