1JFV
X-Ray Structure of oxidised C10S, C15A arsenate reductase from pI258
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030612 | molecular_function | arsenate reductase (thioredoxin) activity |
| A | 0046685 | biological_process | response to arsenic-containing substance |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE LCP A 132 |
| Chain | Residue |
| A | SER10 |
| A | THR11 |
| A | GLY12 |
| A | SER14 |
| A | ALA15 |
| A | ARG16 |
| A | SER17 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 133 |
| Chain | Residue |
| A | SER36 |
| A | THR63 |
| A | ASP65 |
| A | HOH143 |
| A | ASN13 |
| A | GLU21 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01624, ECO:0000305|PubMed:11573087, ECO:0000305|PubMed:12072565 |
| Chain | Residue | Details |
| A | SER10 | |
| A | CYS82 | |
| A | CYS89 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11573087, ECO:0000269|PubMed:12072565, ECO:0000269|PubMed:12682056, ECO:0000269|PubMed:15159594, ECO:0000269|PubMed:16797027 |
| Chain | Residue | Details |
| A | ASN13 | |
| A | SER36 | |
| A | THR63 | |
| A | ASP65 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 14 |
| Details | M-CSA 143 |
| Chain | Residue | Details |
| A | SER10 | electrofuge, electrophile, nucleofuge, nucleophile |
| A | THR63 | |
| A | ASP65 | |
| A | CYS82 | electrofuge, electrophile, hydrogen bond acceptor, nucleofuge, nucleophile |
| A | CYS89 | hydrogen bond acceptor, nucleofuge, nucleophile |
| A | ASP105 | electrostatic stabiliser, hydrogen bond acceptor |
| A | THR11 | electrostatic stabiliser, hydrogen bond donor |
| A | GLY12 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN13 | electrostatic stabiliser, hydrogen bond donor |
| A | SER14 | electrostatic stabiliser, hydrogen bond donor |
| A | ALA15 | electrostatic stabiliser, hydrogen bond donor |
| A | ARG16 | electrostatic stabiliser, hydrogen bond donor |
| A | SER17 | electrostatic stabiliser, hydrogen bond donor |
| A | SER36 |
