1JFJ
NMR SOLUTION STRUCTURE OF AN EF-HAND CALCIUM BINDING PROTEIN FROM ENTAMOEBA HISTOLYTICA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001891 | cellular_component | phagocytic cup |
| A | 0003779 | molecular_function | actin binding |
| A | 0003785 | molecular_function | actin monomer binding |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006897 | biological_process | endocytosis |
| A | 0006909 | biological_process | phagocytosis |
| A | 0031143 | cellular_component | pseudopodium |
| A | 0032231 | biological_process | regulation of actin filament bundle assembly |
| A | 0045859 | biological_process | regulation of protein kinase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050766 | biological_process | positive regulation of phagocytosis |
| A | 0051015 | molecular_function | actin filament binding |
| A | 1905303 | biological_process | positive regulation of macropinocytosis |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DVNGDGAVSyeEV |
| Chain | Residue | Details |
| A | ASP10-VAL22 | |
| A | ASP46-PHE58 | |
| A | ASP85-VAL97 | |
| A | ASP117-PHE129 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 31 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 26 |
| Details | Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11724551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17554780","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20550906","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23782698","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22906057","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1JFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2M7M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LI6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PX1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3QJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ULG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23782698","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2M7N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11724551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23782698","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2M7N","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
