1JFI

Crystal Structure of the NC2-TBP-DNA Ternary Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046982	molecular_function	protein heterodimerization activity
B	0000122	biological_process	negative regulation of transcription by RNA polymerase II
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
B	0006357	biological_process	regulation of transcription by RNA polymerase II
B	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
B	0017025	molecular_function	TBP-class protein binding
B	0017054	cellular_component	negative cofactor 2 complex
B	0017055	biological_process	negative regulation of RNA polymerase II transcription preinitiation complex assembly
B	0045995	biological_process	regulation of embryonic development
B	0046982	molecular_function	protein heterodimerization activity
B	0051123	biological_process	RNA polymerase II preinitiation complex assembly
B	0051302	biological_process	regulation of cell division
B	0051726	biological_process	regulation of cell cycle
B	0072686	cellular_component	mitotic spindle
B	0090043	biological_process	regulation of tubulin deacetylation
B	0090575	cellular_component	RNA polymerase II transcription regulator complex
B	0140223	molecular_function	general transcription initiation factor activity
B	0140672	cellular_component	ATAC complex
C	0003677	molecular_function	DNA binding
C	0006352	biological_process	DNA-templated transcription initiation

Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	63
Details	Domain: {"description":"Histone-fold","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	3
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Chain

Residue

Details

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27193682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IYD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details