1JDZ
CRYSTAL STRUCTURE OF 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE WITH FORMYCIN B AND SULFATE ION
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009164 | biological_process | nucleoside catabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0017061 | molecular_function | S-methyl-5-thioadenosine phosphorylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009164 | biological_process | nucleoside catabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0017061 | molecular_function | S-methyl-5-thioadenosine phosphorylase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0009164 | biological_process | nucleoside catabolic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0017061 | molecular_function | S-methyl-5-thioadenosine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 250 |
| Chain | Residue |
| A | GLY21 |
| A | ARG25 |
| A | ARG43 |
| A | ARG86 |
| A | GLY88 |
| A | THR89 |
| A | FMB270 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 255 |
| Chain | Residue |
| B | ARG86 |
| B | GLY88 |
| B | THR89 |
| B | FMB275 |
| B | HOH317 |
| C | ARG43 |
| B | GLY21 |
| B | ARG25 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 260 |
| Chain | Residue |
| B | ARG43 |
| C | GLY21 |
| C | ARG86 |
| C | GLY88 |
| C | THR89 |
| C | FMB280 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE FMB A 270 |
| Chain | Residue |
| A | HIS5 |
| A | ARG43 |
| A | ILE64 |
| A | ARG86 |
| A | THR89 |
| A | THR90 |
| A | GLY91 |
| A | VAL179 |
| A | GLU180 |
| A | MET181 |
| A | GLU182 |
| A | SER204 |
| A | SO4250 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE FMB B 275 |
| Chain | Residue |
| B | ILE64 |
| B | ARG86 |
| B | THR89 |
| B | THR90 |
| B | GLY91 |
| B | VAL179 |
| B | GLU180 |
| B | GLU182 |
| B | SER204 |
| B | ASP205 |
| B | SO4255 |
| B | HOH317 |
| C | HIS5 |
| C | ARG43 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE FMB C 280 |
| Chain | Residue |
| B | HIS5 |
| B | ARG43 |
| C | ILE64 |
| C | ARG86 |
| C | THR89 |
| C | THR90 |
| C | GLY91 |
| C | PHE160 |
| C | VAL179 |
| C | GLU180 |
| C | MET181 |
| C | GLU182 |
| C | SER204 |
| C | ASP205 |
| C | SO4260 |
Functional Information from PROSITE/UniProt
| site_id | PS01232 |
| Number of Residues | 16 |
| Details | PNP_UDP_1 Purine and other phosphorylases family 1 signature. ThGIGgPSiAIvleEL |
| Chain | Residue | Details |
| A | THR61-LEU76 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11489901","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"11489901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JE0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11489901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JE0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"11489901","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"11489901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JDT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JE1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cg6 |
| Chain | Residue | Details |
| A | LEU207 | |
| A | ASP205 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cg6 |
| Chain | Residue | Details |
| B | LEU207 | |
| B | ASP205 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cg6 |
| Chain | Residue | Details |
| C | LEU207 | |
| C | ASP205 |
