1JC4
Crystal Structure of Se-Met Methylmalonyl-CoA Epimerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004493 | molecular_function | methylmalonyl-CoA epimerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046491 | biological_process | L-methylmalonyl-CoA metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004493 | molecular_function | methylmalonyl-CoA epimerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0046491 | biological_process | L-methylmalonyl-CoA metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004493 | molecular_function | methylmalonyl-CoA epimerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0046491 | biological_process | L-methylmalonyl-CoA metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004493 | molecular_function | methylmalonyl-CoA epimerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0046491 | biological_process | L-methylmalonyl-CoA metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 201 |
| Chain | Residue |
| A | THR58 |
| A | GLU59 |
| A | HIS60 |
| A | MSE61 |
| B | THR58 |
| B | HIS60 |
| B | MSE61 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 202 |
| Chain | Residue |
| C | HIS60 |
| C | MSE61 |
| D | THR58 |
| D | GLU59 |
| D | HIS60 |
| D | MSE61 |
| C | THR58 |
| C | GLU59 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | GLU48 |
| A | GLN65 |
| A | GLY121 |
| A | THR122 |
| A | ILE127 |
| A | GLU141 |
| A | HOH205 |
| A | HOH209 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 204 |
| Chain | Residue |
| B | HIS12 |
| B | GLU48 |
| B | GLN65 |
| B | THR122 |
| B | ILE127 |
| B | GLU141 |
| B | HOH205 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 205 |
| Chain | Residue |
| C | HIS12 |
| C | GLU48 |
| C | GLN65 |
| C | GLY121 |
| C | THR122 |
| C | ILE127 |
| C | GLU141 |
| C | HOH206 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 206 |
| Chain | Residue |
| D | GLU48 |
| D | GLN65 |
| D | GLY121 |
| D | THR122 |
| D | GLU141 |
| D | HOH207 |
| D | HOH222 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| A | GLU141 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| B | GLU141 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| C | GLU141 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| D | GLU141 |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 33 |
| Chain | Residue | Details |
| A | ALA16 | metal ligand |
| A | ALA52 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ALA81 | metal ligand |
| A | VAL111 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 33 |
| Chain | Residue | Details |
| B | ALA16 | metal ligand |
| B | ALA52 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | ALA81 | metal ligand |
| B | VAL111 | metal ligand |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 33 |
| Chain | Residue | Details |
| C | ALA16 | metal ligand |
| C | ALA52 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | ALA81 | metal ligand |
| C | VAL111 | metal ligand |
| site_id | MCSA4 |
| Number of Residues | 4 |
| Details | M-CSA 33 |
| Chain | Residue | Details |
| D | ALA16 | metal ligand |
| D | ALA52 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | ALA81 | metal ligand |
| D | VAL111 | metal ligand |
