Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EOH A 572 |
| Chain | Residue |
| A | SER1 |
| A | ASP2 |
| A | GLU62 |
| A | ILE104 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EOH A 573 |
| Chain | Residue |
| A | VAL310 |
| A | SER319 |
| A | HOH420 |
| A | HOH458 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EOH A 574 |
| Chain | Residue |
| A | ASN263 |
| A | PHE264 |
| A | ASP265 |
| A | HOH429 |
| A | GLY200 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EOH A 575 |
| Chain | Residue |
| A | GLY85 |
| A | ASN294 |
| A | ILE298 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EOH A 576 |
| Chain | Residue |
| A | ALA130 |
| A | ASP131 |
| A | GLU132 |
| A | GLY134 |
| A | TYR135 |
| A | HOH507 |
| B | ILE337 |
| B | SER339 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EOH A 577 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VVIDTGSSDLWV |
| Chain | Residue | Details |
| A | VAL29-VAL40 | |
| A | VAL215-PHE226 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 307 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP32 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | SER35 | |
| A | ASP218 | |
| A | ASP32 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP218 | |
| A | ASP32 | |
| A | THR33 | |
| A | SER219 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER35 | |
| A | ASP218 | |
| A | ASP32 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER35 | |
| A | TYR84 | |
| A | ASP218 | |
| A | ASP32 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR221 | |
| A | ASP218 | |
| A | ASP32 | |
| A | THR33 | |
