1J4G
crystal structure analysis of the trichosanthin delta C7
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006952 | biological_process | defense response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0050688 | biological_process | regulation of defense response to virus |
| A | 0090729 | molecular_function | toxin activity |
| B | 0006952 | biological_process | defense response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017148 | biological_process | negative regulation of translation |
| B | 0030598 | molecular_function | rRNA N-glycosylase activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0050688 | biological_process | regulation of defense response to virus |
| B | 0090729 | molecular_function | toxin activity |
| C | 0006952 | biological_process | defense response |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0017148 | biological_process | negative regulation of translation |
| C | 0030598 | molecular_function | rRNA N-glycosylase activity |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0050688 | biological_process | regulation of defense response to virus |
| C | 0090729 | molecular_function | toxin activity |
| D | 0006952 | biological_process | defense response |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0017148 | biological_process | negative regulation of translation |
| D | 0030598 | molecular_function | rRNA N-glycosylase activity |
| D | 0035821 | biological_process | modulation of process of another organism |
| D | 0050688 | biological_process | regulation of defense response to virus |
| D | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 1201 |
| Chain | Residue |
| B | HOH1232 |
| B | HOH1252 |
| B | HOH1301 |
| B | HOH1307 |
| B | HOH1316 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 1202 |
| Chain | Residue |
| A | HOH1379 |
| A | HOH1332 |
| A | HOH1335 |
| A | HOH1343 |
| A | HOH1346 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA D 1203 |
| Chain | Residue |
| D | HOH1225 |
| D | HOH1339 |
| D | HOH1345 |
| D | HOH1362 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA C 1204 |
| Chain | Residue |
| C | LEU240 |
| C | HOH1277 |
| C | HOH1372 |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqSTsEAARYKfIEqqI |
| Chain | Residue | Details |
| A | ILE155-ILE171 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| A | GLU160 | |
| A | ARG163 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| B | GLU160 | |
| B | ARG163 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| C | GLU160 | |
| C | ARG163 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1abr |
| Chain | Residue | Details |
| D | GLU160 | |
| D | ARG163 |
