1J4B

Recombinant Mouse-Muscle Adenylosuccinate Synthetase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003924	molecular_function	GTPase activity
A	0004019	molecular_function	adenylosuccinate synthase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0006163	biological_process	purine nucleotide metabolic process
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006167	biological_process	AMP biosynthetic process
A	0006531	biological_process	aspartate metabolic process
A	0006541	biological_process	glutamine metabolic process
A	0014850	biological_process	response to muscle activity
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0042594	biological_process	response to starvation
A	0042802	molecular_function	identical protein binding
A	0044208	biological_process	'de novo' AMP biosynthetic process
A	0044209	biological_process	AMP salvage
A	0046040	biological_process	IMP metabolic process
A	0046872	molecular_function	metal ion binding
A	0051015	molecular_function	actin filament binding
A	0071257	biological_process	cellular response to electrical stimulus
A	0071466	biological_process	cellular response to xenobiotic stimulus

Functional Information from PROSITE/UniProt

site_id	PS00513
Number of Residues	12
Details	ADENYLOSUCCIN_SYN_2 Adenylosuccinate synthetase active site. GIGPtYssKaaR

Chain	Residue	Details
A	GLY166-ARG177

site_id	PS01266
Number of Residues	8
Details	ADENYLOSUCCIN_SYN_1 Adenylosuccinate synthetase GTP-binding site. QWGDEGKG

Chain	Residue	Details
A	GLN40-GLY47

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255\|HAMAP-Rule:MF_03126

Chain	Residue	Details
A	ASP43

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255\|HAMAP-Rule:MF_03126

Chain	Residue	Details
A	HIS71

site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_03126, ECO:0000269\|PubMed:12004071

Chain	Residue	Details
A	ASN68

site_id	SWS_FT_FI6
Number of Residues	4
Details	BINDING: in other chain => ECO:0000255\|HAMAP-Rule:MF_03126, ECO:0000269\|PubMed:12004071