1J34
Crystal Structure of Mg(II)-and Ca(II)-bound Gla Domain of Factor IX Complexed with Binding Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0090729 | molecular_function | toxin activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090729 | molecular_function | toxin activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 501 |
| Chain | Residue |
| A | GLU98 |
| C | CGU426 |
| C | CGU430 |
| C | HOH1006 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 502 |
| Chain | Residue |
| B | HOH804 |
| C | CGU408 |
| C | CGU427 |
| C | CGU430 |
| C | HOH807 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 503 |
| Chain | Residue |
| C | CGU408 |
| C | CGU417 |
| C | CGU427 |
| C | CGU430 |
| C | HOH803 |
| C | HOH805 |
| C | HOH810 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 504 |
| Chain | Residue |
| C | TYR401 |
| C | ASN402 |
| C | CGU407 |
| C | CGU408 |
| C | CGU417 |
| C | CGU427 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 505 |
| Chain | Residue |
| C | TYR401 |
| C | CGU407 |
| C | CGU417 |
| C | CGU421 |
| C | HOH808 |
| C | HOH816 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 506 |
| Chain | Residue |
| C | CGU421 |
| C | HOH646 |
| C | HOH813 |
| C | HOH817 |
| C | HOH847 |
| C | HOH1011 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 507 |
| Chain | Residue |
| C | CGU415 |
| C | CGU420 |
| C | HOH821 |
| C | HOH826 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG C 508 |
| Chain | Residue |
| C | CGU436 |
| C | CGU440 |
| C | HOH802 |
| C | HOH806 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 511 |
| Chain | Residue |
| A | SER41 |
| A | GLU43 |
| A | GLU47 |
| A | GLU128 |
| A | HOH809 |
| A | HOH837 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 512 |
| Chain | Residue |
| B | SER241 |
| B | GLN243 |
| B | GLU247 |
| B | GLU320 |
| B | HOH818 |
| B | HOH820 |
Functional Information from PROSITE/UniProt
| site_id | PS00011 |
| Number of Residues | 26 |
| Details | GLA_1 Vitamin K-dependent carboxylation domain. EckEEkCsfeearEvfentektte.FW |
| Chain | Residue | Details |
| C | CGU417-TRP442 |
| site_id | PS00615 |
| Number of Residues | 26 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CLgleketgfrk..WVNIYCgqqnp.FVC |
| Chain | Residue | Details |
| A | CYS102-CYS127 | |
| B | CYS296-CYS319 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 250 |
| Details | Domain: {"description":"C-type lectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00040","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10339409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12695512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16165155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J34","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X2T","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10339409","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12695512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16165155","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9187649","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IXX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J34","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1J35","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X2T","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
