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1IY9

Crystal structure of spermidine synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004766molecular_functionspermidine synthase activity
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006596biological_processpolyamine biosynthetic process
A0008295biological_processspermidine biosynthetic process
A0016740molecular_functiontransferase activity
B0003824molecular_functioncatalytic activity
B0004766molecular_functionspermidine synthase activity
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006596biological_processpolyamine biosynthetic process
B0008295biological_processspermidine biosynthetic process
B0016740molecular_functiontransferase activity
C0003824molecular_functioncatalytic activity
C0004766molecular_functionspermidine synthase activity
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006596biological_processpolyamine biosynthetic process
C0008295biological_processspermidine biosynthetic process
C0016740molecular_functiontransferase activity
D0003824molecular_functioncatalytic activity
D0004766molecular_functionspermidine synthase activity
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006596biological_processpolyamine biosynthetic process
D0008295biological_processspermidine biosynthetic process
D0016740molecular_functiontransferase activity
Functional Information from PROSITE/UniProt
site_idPS01330
Number of Residues14
DetailsPABS_1 Polyamine biosynthesis (PABS) domain signature. VLVVGGGdGgvIrE
ChainResidueDetails
AVAL80-GLU93

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues932
DetailsDomain: {"description":"PABS","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsActive site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues36
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00198","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246333

PDB entries from 2025-12-17

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