1IXX

CRYSTAL STRUCTURE OF COAGULATION FACTORS IX/X-BINDING PROTEIN (IX/X-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0035821	biological_process	modulation of process of another organism
A	0046872	molecular_function	metal ion binding
A	0090729	molecular_function	toxin activity
B	0005509	molecular_function	calcium ion binding
B	0005576	cellular_component	extracellular region
B	0035821	biological_process	modulation of process of another organism
B	0046872	molecular_function	metal ion binding
B	0090729	molecular_function	toxin activity
C	0005576	cellular_component	extracellular region
C	0035821	biological_process	modulation of process of another organism
C	0046872	molecular_function	metal ion binding
C	0090729	molecular_function	toxin activity
D	0005509	molecular_function	calcium ion binding
D	0005576	cellular_component	extracellular region
D	0035821	biological_process	modulation of process of another organism
D	0046872	molecular_function	metal ion binding
D	0090729	molecular_function	toxin activity
E	0005576	cellular_component	extracellular region
E	0035821	biological_process	modulation of process of another organism
E	0046872	molecular_function	metal ion binding
E	0090729	molecular_function	toxin activity
F	0005509	molecular_function	calcium ion binding
F	0005576	cellular_component	extracellular region
F	0035821	biological_process	modulation of process of another organism
F	0046872	molecular_function	metal ion binding
F	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 130

Chain	Residue
A	SER41
A	GLU43
A	GLU47
A	GLU128
A	HOH147

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA B 124

Chain	Residue
B	SER41
B	GLN43
B	GLU47
B	GLU120

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA C 130

Chain	Residue
C	SER41
C	GLU43
C	GLU47
C	GLU128
C	HOH145

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA D 124

Chain	Residue
D	SER41
D	GLN43
D	GLU47
D	GLU120

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA E 130

Chain	Residue
E	SER41
E	GLU43
E	GLU47
E	GLU128

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA F 124

Chain	Residue
F	SER41
F	GLN43
F	GLU47
F	GLU120

---

site_id	S1
Number of Residues	5
Details	CALCIUM-BINDING SITE.

Chain	Residue
A	SER41
A	GLU43
A	GLU47
A	GLU128
A	HOH147

---

site_id	S2
Number of Residues	4
Details	CALCIUM-BINDING SITE.

Chain	Residue
B	SER41
B	GLN43
B	GLU47
B	GLU120

---

site_id	S3
Number of Residues	5
Details	CALCIUM-BINDING SITE.

Chain	Residue
C	SER41
C	GLU43
C	GLU47
C	GLU128
C	HOH145

---

site_id	S4
Number of Residues	4
Details	CALCIUM-BINDING SITE.

Chain	Residue
D	SER41
D	GLN43
D	GLU47
D	GLU120

---

site_id	S5
Number of Residues	5
Details	CALCIUM-BINDING SITE.

Chain	Residue
E	SER41
E	GLU43
E	GLU47
E	GLU128
E	HOH154

---

site_id	S6
Number of Residues	4
Details	CALCIUM-BINDING SITE.

Chain	Residue
F	SER41
F	GLN43
F	GLU47
F	GLU120

---

Functional Information from PROSITE/UniProt

site_id	PS00615
Number of Residues	26
Details	C_TYPE_LECTIN_1 C-type lectin domain signature. CLgleketdfrk..WVNIYCgqqnp.FVC

Chain	Residue	Details
A	CYS102-CYS127
B	CYS96-CYS119

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:10339409, ECO:0000269|PubMed:12695512, ECO:0000269|PubMed:16165155, ECO:0000269|PubMed:9187649, ECO:0007744|PDB:1BJ3, ECO:0007744|PDB:1IXX, ECO:0007744|PDB:1J34, ECO:0007744|PDB:1J35, ECO:0007744|PDB:1X2T

Chain	Residue	Details
B	SER41
F	GLN43
F	GLU47
F	GLU120
B	GLN43
B	GLU47
B	GLU120
D	SER41
D	GLN43
D	GLU47
D	GLU120
F	SER41

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