1IXR

RuvA-RuvB complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000400	molecular_function	four-way junction DNA binding
A	0003677	molecular_function	DNA binding
A	0003678	molecular_function	DNA helicase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0006974	biological_process	DNA damage response
A	0009378	molecular_function	four-way junction helicase activity
A	0009379	cellular_component	Holliday junction helicase complex
A	0048476	cellular_component	Holliday junction resolvase complex
B	0000400	molecular_function	four-way junction DNA binding
B	0003677	molecular_function	DNA binding
B	0003678	molecular_function	DNA helicase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0006974	biological_process	DNA damage response
B	0009378	molecular_function	four-way junction helicase activity
B	0009379	cellular_component	Holliday junction helicase complex
B	0048476	cellular_component	Holliday junction resolvase complex
C	0000166	molecular_function	nucleotide binding
C	0000400	molecular_function	four-way junction DNA binding
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0006974	biological_process	DNA damage response
C	0009378	molecular_function	four-way junction helicase activity
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0048476	cellular_component	Holliday junction resolvase complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ANP C 313

Chain	Residue
C	ARG7
C	ARG205
C	LYS208
C	TYR14
C	ILE15
C	GLY48
C	GLY50
C	LYS51
C	THR52
C	THR53
C	MET204

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	124
Details	Region: {"description":"Domain I","evidences":[{"source":"HAMAP-Rule","id":"MF_00031","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	128
Details	Region: {"description":"Domain II","evidences":[{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Motif: {"description":"Acidic pin","evidences":[{"source":"UniProtKB","id":"P0A809","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	11
Details	Region: {"description":"Flexible linker","evidences":[{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	47
Details	Region: {"description":"Domain III","evidences":[{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	70
Details	Region: {"description":"Small ATPAse domain (RuvB-S)","evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IXR","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IXR","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI14
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1nsf

Chain	Residue	Details
C	LYS51

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1nsf

Chain	Residue	Details
C	THR146
C	ARG205

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site_id	MCSA1
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
C	LYS51
C	THR52
C	ASP97
C	THR146	electrostatic stabiliser
C	ARG205	electrostatic stabiliser

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