1IXA

THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00010
Number of Residues	12
Details	ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDdinsYeCwC

Chain	Residue	Details
A	CYS62-CYS73

---

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CwCpfGfeGKnC

Chain	Residue	Details
A	CYS71-CYS82

---

site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CwCpfGFegkn....C

Chain	Residue	Details
A	CYS71-CYS82

---

site_id	PS01187
Number of Residues	25
Details	EGF_CA Calcium-binding EGF-like domain signature. DgDQCesnp..........Clnggs..CkDdinsYeC

Chain	Residue	Details
A	ASP47-CYS71

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:7606779, ECO:0007744|PDB:1EDM

Chain	Residue	Details
A	ASP47
A	GLY48
A	GLN50
A	ASP64
A	ASP65

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: (3R)-3-hydroxyaspartate => ECO:0000269|PubMed:6688526

Chain	Residue	Details
A	ASP64

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|Ref.28

Chain	Residue	Details
A	SER68

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: O-linked (Glc...) serine => ECO:0000269|PubMed:2129367, ECO:0000269|PubMed:2511201, ECO:0000269|PubMed:25456591

Chain	Residue	Details
A	SER53

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: O-linked (Fuc...) serine => ECO:0000269|PubMed:1517205, ECO:0000269|PubMed:25456591

Chain	Residue	Details
A	SER61

---