1IWP

Glycerol Dehydratase-cyanocobalamin Complex of Klebsiella pneumoniae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016829	molecular_function	lyase activity
A	0016836	molecular_function	hydro-lyase activity
A	0031419	molecular_function	cobalamin binding
A	0046405	molecular_function	glycerol dehydratase activity
B	0016829	molecular_function	lyase activity
B	0046405	molecular_function	glycerol dehydratase activity
B	0050215	molecular_function	propanediol dehydratase activity
E	0016829	molecular_function	lyase activity
E	0046405	molecular_function	glycerol dehydratase activity
E	0050215	molecular_function	propanediol dehydratase activity
G	0016829	molecular_function	lyase activity
G	0046405	molecular_function	glycerol dehydratase activity
G	0050215	molecular_function	propanediol dehydratase activity
L	0003824	molecular_function	catalytic activity
L	0016829	molecular_function	lyase activity
L	0016836	molecular_function	hydro-lyase activity
L	0031419	molecular_function	cobalamin binding
L	0046405	molecular_function	glycerol dehydratase activity
M	0016829	molecular_function	lyase activity
M	0046405	molecular_function	glycerol dehydratase activity
M	0050215	molecular_function	propanediol dehydratase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K A 1603

Chain	Residue
A	GLN142
A	GLU171
A	GLU222
A	GLN297
A	SER363
A	PGO1602

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PGO A 1602

Chain	Residue
A	THR223
A	GLN297
A	SER302
A	ASP336
A	GLN337
A	SER363
A	PHE375
A	K1603
A	HOH1840
A	HIS144
A	GLU171
A	GLU222

---

site_id	AC3
Number of Residues	41
Details	BINDING SITE FOR RESIDUE B12 B 1601

Chain	Residue
A	THR173
A	VAL174
A	GLY175
A	ALA177
A	SER203
A	GLU206
A	THR223
A	ASP235
A	LEU268
A	MET269
A	SER302
A	GLN337
A	MET374
A	PHE375
A	HOH1639
A	HOH1723
B	ASP79
B	VAL80
B	SER81
B	LYS102
B	THR104
B	LEU115
B	ASN117
B	LEU120
B	SER122
B	GLN123
B	ALA124
B	VAL159
B	ARG160
B	PHE163
B	MET164
B	ALA167
B	HOH1602
B	HOH1603
B	HOH1604
B	HOH1608
B	HOH1610
B	HOH1613
B	HOH1614
B	HOH1618
B	HOH1636

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE K L 2603

Chain	Residue
L	GLN142
L	GLU171
L	GLU222
L	GLN297
L	SER363
L	PGO2602

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PGO L 2602

Chain	Residue
L	HIS144
L	GLU171
L	GLU222
L	THR223
L	GLN297
L	SER302
L	ASP336
L	GLN337
L	SER363
L	PHE375
L	K2603

---

site_id	AC6
Number of Residues	43
Details	BINDING SITE FOR RESIDUE B12 E 2601

Chain	Residue
E	HOH2662
L	THR173
L	VAL174
L	GLY175
L	ALA177
L	SER203
L	GLU206
L	THR223
L	ASP235
L	LEU268
L	MET269
L	SER302
L	GLN337
L	MET374
L	PHE375
L	HOH2635
L	HOH2667
L	HOH2750
L	HOH2754
L	HOH2788
E	ASP79
E	VAL80
E	SER81
E	LYS102
E	THR104
E	LEU115
E	ASN117
E	LEU120
E	SER122
E	GLN123
E	ALA124
E	VAL159
E	ARG160
E	PHE163
E	MET164
E	ALA167
E	HOH2602
E	HOH2603
E	HOH2604
E	HOH2611
E	HOH2612
E	HOH2637
E	HOH2651

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1dio

Chain	Residue	Details
A	GLN297
A	ASP336
A	HIS144
A	GLU171

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1dio

Chain	Residue	Details
L	GLN297
L	ASP336
L	HIS144
L	GLU171

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