1ITH
STRUCTURE DETERMINATION AND REFINEMENT OF HOMOTETRAMERIC HEMOGLOBIN FROM URECHIS CAUPO AT 2.5 ANGSTROMS RESOLUTION
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CYN A 142 |
| Chain | Residue |
| A | PHE44 |
| A | GLN64 |
| A | VAL68 |
| A | HEM143 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CYN B 142 |
| Chain | Residue |
| B | GLN64 |
| B | HEM143 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HEM A 143 |
| Chain | Residue |
| A | LYS46 |
| A | GLN64 |
| A | LYS90 |
| A | SER93 |
| A | HIS94 |
| A | ILE99 |
| A | HIS103 |
| A | PHE104 |
| A | CYN142 |
| A | TYR33 |
| A | PHE43 |
| A | PHE44 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM B 143 |
| Chain | Residue |
| B | TYR33 |
| B | PHE43 |
| B | LYS46 |
| B | GLN64 |
| B | VAL68 |
| B | TYR71 |
| B | LYS90 |
| B | SER93 |
| B | HIS94 |
| B | ILE99 |
| B | HIS103 |
| B | PHE104 |
| B | LEU107 |
| B | CYN142 |
| B | HOH448 |
| B | HOH504 |
| B | HOH604 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 280 |
| Details | Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"8133523","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ITH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
