Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1IRP

SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN

Functional Information from GO Data
ChainGOidnamespacecontents
A0002437biological_processinflammatory response to antigenic stimulus
A0005125molecular_functioncytokine activity
A0005149molecular_functioninterleukin-1 receptor binding
A0005150molecular_functioninterleukin-1, type I receptor binding
A0005151molecular_functioninterleukin-1, type II receptor binding
A0005152molecular_functioninterleukin-1 receptor antagonist activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006629biological_processlipid metabolic process
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007165biological_processsignal transduction
A0030073biological_processinsulin secretion
A0031982cellular_componentvesicle
A0034115biological_processnegative regulation of heterotypic cell-cell adhesion
A0045352molecular_functioninterleukin-1 type I receptor antagonist activity
A0045353molecular_functioninterleukin-1 type II receptor antagonist activity
A0051384biological_processresponse to glucocorticoid
A0070062cellular_componentextracellular exosome
A2000660biological_processnegative regulation of interleukin-1-mediated signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00253
Number of Residues21
DetailsINTERLEUKIN_1 Interleukin-1 signature. FeSAacPgwFLCTameadqpV
ChainResidueDetails
APHE112-VAL132

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:2137200
ChainResidueDetails
AASN85

227111

PDB entries from 2024-11-06

PDB statisticsPDBj update infoContact PDBjnumon