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1IRG

INTERFERON REGULATORY FACTOR-2 DNA BINDING DOMAIN, NMR, 20 STRUCTURES

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WlNkekkiFqIPWmHaarhgwdvekDapLFRnWA
ChainResidueDetails
ATRP26-ALA59

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues108
DetailsDNA_BIND: IRF tryptophan pentad repeat => ECO:0000255|PROSITE-ProRule:PRU00840
ChainResidueDetails
AARG5-PRO113

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P14316
ChainResidueDetails
ALYS75
ALYS78

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PDB entries from 2024-04-24

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