1IRF

INTERFERON REGULATORY FACTOR-2 DNA BINDING DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00601
Number of Residues	34
Details	IRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WlNkekkiFqIPWmHaarhgwdvekDapLFRnWA

Chain	Residue	Details
A	TRP26-ALA59

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	108
Details	DNA_BIND: IRF tryptophan pentad repeat => ECO:0000255|PROSITE-ProRule:PRU00840

Chain	Residue	Details
A	ARG5-PRO113

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P14316

Chain	Residue	Details
A	LYS75
A	LYS78

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