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1IP3

G68A HUMAN LYSOZYME

Functional Information from GO Data
ChainGOidnamespacecontents
A0003796molecular_functionlysozyme activity
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006954biological_processinflammatory response
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0019730biological_processantimicrobial humoral response
A0031640biological_processkilling of cells of another organism
A0035578cellular_componentazurophil granule lumen
A0035580cellular_componentspecific granule lumen
A0042742biological_processdefense response to bacterium
A0042802molecular_functionidentical protein binding
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0070062cellular_componentextracellular exosome
A1904724cellular_componenttertiary granule lumen
B0003796molecular_functionlysozyme activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006954biological_processinflammatory response
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0019730biological_processantimicrobial humoral response
B0031640biological_processkilling of cells of another organism
B0035578cellular_componentazurophil granule lumen
B0035580cellular_componentspecific granule lumen
B0042742biological_processdefense response to bacterium
B0042802molecular_functionidentical protein binding
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0070062cellular_componentextracellular exosome
B1904724cellular_componenttertiary granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 999
ChainResidue
ASER61
ACYS65
AALA73
AVAL74
AASN75
AHOH670

site_idAC2
Number of Residues11
DetailsBINDING SITE FOR RESIDUE SO4 A 131
ChainResidue
AHOH341
AHOH346
AHOH400
AHOH667
BHOH209
BARG505
BLYS533
BTYR538
ATYR20
ALYS97
AHOH223

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 132
ChainResidue
AASN66
ASER80
AHOH165
AHOH202
AHOH239
AHOH366
AHOH387
AHOH692
BTHR543

site_idAC4
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 144
ChainResidue
ALYS69
AASN88
AHOH257
AHOH336
AHOH340
AHOH353
BHOH448
BLYS501
BVAL502

Functional Information from PROSITE/UniProt
site_idPS00128
Number of Residues19
DetailsGLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC
ChainResidueDetails
ACYS77-CYS95

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE:
ChainResidueDetails
AGLU35
AASP53
BGLU535
BASP553

219869

PDB entries from 2024-05-15

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