Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1IO9

THERMOPHILIC CYTOCHROME P450 (CYP119) FROM SULFOLOBUS SOLFATARICUS: HIGH RESOLUTION STRUCTURAL ORIGIN OF ITS THERMOSTABILITY AND FUNCTIONAL PROPERTIES

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0004601molecular_functionperoxidase activity
A0005506molecular_functioniron ion binding
A0005737cellular_componentcytoplasm
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0046872molecular_functionmetal ion binding
A0098869biological_processcellular oxidant detoxification
A0140825molecular_functionlactoperoxidase activity
B0004497molecular_functionmonooxygenase activity
B0004601molecular_functionperoxidase activity
B0005506molecular_functioniron ion binding
B0005737cellular_componentcytoplasm
B0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
B0020037molecular_functionheme binding
B0046872molecular_functionmetal ion binding
B0098869biological_processcellular oxidant detoxification
B0140825molecular_functionlactoperoxidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues22
DetailsBINDING SITE FOR RESIDUE HEM A 401
ChainResidue
AMET68
ATHR214
ALEU217
ATHR257
AARG259
ASER309
APHE310
AILE314
AHIS315
ACYS317
ALEU318
ALEU69
AGLY319
AHOH402
AHOH411
AHIS76
AARG80
ALEU205
ALEU206
AALA209
AGLY210
ATHR213

site_idAC2
Number of Residues21
DetailsBINDING SITE FOR RESIDUE HEM B 901
ChainResidue
BHOH38
BMET568
BLEU569
BHIS576
BARG580
BLEU705
BLEU706
BALA709
BGLY710
BTHR713
BTHR757
BARG759
BSER809
BPHE810
BGLY811
BILE814
BHIS815
BCYS817
BGLY819
BALA823
BHOH902

Functional Information from PROSITE/UniProt
site_idPS00086
Number of Residues10
DetailsCYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGsGIHLCLG
ChainResidueDetails
APHE310-GLY319

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBINDING: BINDING => ECO:0000269|PubMed:10859321, ECO:0000269|PubMed:10957637
ChainResidueDetails
AHIS76
BHIS815
AARG80
ATHR257
AARG259
AHIS315
BHIS576
BARG580
BTHR757
BARG759

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: axial binding residue
ChainResidueDetails
ACYS317
BCYS817

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1akd
ChainResidueDetails
AGLU212
ATHR213

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1akd
ChainResidueDetails
BTHR713
BGLU712

223166

PDB entries from 2024-07-31

PDB statisticsPDBj update infoContact PDBjnumon