1IMV
2.85 A crystal structure of PEDF
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001822 | biological_process | kidney development |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005604 | cellular_component | basement membrane |
| A | 0005615 | cellular_component | extracellular space |
| A | 0007614 | biological_process | short-term memory |
| A | 0010447 | biological_process | response to acidic pH |
| A | 0010596 | biological_process | negative regulation of endothelial cell migration |
| A | 0010629 | biological_process | negative regulation of gene expression |
| A | 0010976 | biological_process | positive regulation of neuron projection development |
| A | 0016525 | biological_process | negative regulation of angiogenesis |
| A | 0030424 | cellular_component | axon |
| A | 0031012 | cellular_component | extracellular matrix |
| A | 0042470 | cellular_component | melanosome |
| A | 0042698 | biological_process | ovulation cycle |
| A | 0043025 | cellular_component | neuronal cell body |
| A | 0043203 | cellular_component | axon hillock |
| A | 0046685 | biological_process | response to arsenic-containing substance |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0050769 | biological_process | positive regulation of neurogenesis |
| A | 0060041 | biological_process | retina development in camera-type eye |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071279 | biological_process | cellular response to cobalt ion |
| A | 0071300 | biological_process | cellular response to retinoic acid |
| A | 0071333 | biological_process | cellular response to glucose stimulus |
| A | 0071549 | biological_process | cellular response to dexamethasone stimulus |
| A | 1901652 | biological_process | response to peptide |
Functional Information from PROSITE/UniProt
| site_id | PS00284 |
| Number of Residues | 11 |
| Details | SERPIN Serpins signature. YHLNQPFIFvL |
| Chain | Residue | Details |
| A | TYR368-LEU378 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by CK2","evidences":[{"source":"PubMed","id":"15374885","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"15374885","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","evidences":[{"source":"PubMed","id":"11562499","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
