1ILW

Crystal Structure of Pyrazinamidase/Nicotinamidase of Pyrococcus horikoshii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008936	molecular_function	nicotinamidase activity
A	0016787	molecular_function	hydrolase activity
A	0016811	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0046872	molecular_function	metal ion binding

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1nf9

Chain	Residue	Details
A	ASP10

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site_id	MCSA1
Number of Residues	9
Details	M-CSA 716

Chain	Residue	Details
A	ASP10	proton acceptor, proton donor
A	ASP52	metal ligand
A	HIS54	metal ligand
A	SER60	electrostatic stabiliser
A	HIS71	metal ligand
A	LYS94	electrostatic stabiliser
A	GLU101	electrostatic stabiliser
A	ALA129	electrostatic stabiliser
A	CYS133	electrostatic stabiliser

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