1IFX
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH TWO MOLECULES DEAMIDO-NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008795 | molecular_function | NAD+ synthase activity |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016879 | molecular_function | ligase activity, forming carbon-nitrogen bonds |
| A | 0030435 | biological_process | sporulation resulting in formation of a cellular spore |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008795 | molecular_function | NAD+ synthase activity |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0016879 | molecular_function | ligase activity, forming carbon-nitrogen bonds |
| B | 0030435 | biological_process | sporulation resulting in formation of a cellular spore |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DND B 7000 |
| Chain | Residue |
| A | TYR32 |
| B | PHE1168 |
| B | THR1169 |
| B | LYS1170 |
| B | ASP1173 |
| B | HIS1257 |
| B | LYS1258 |
| B | HOH6091 |
| B | HOH6181 |
| B | HOH6214 |
| A | THR36 |
| A | TYR144 |
| A | LEU153 |
| A | ASP177 |
| B | PHE1129 |
| B | ASN1133 |
| B | ARG1137 |
| B | PHE1167 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DND A 8000 |
| Chain | Residue |
| A | PHE129 |
| A | ASN133 |
| A | ARG137 |
| A | PHE167 |
| A | PHE168 |
| A | THR169 |
| A | LYS170 |
| A | HIS257 |
| A | LYS258 |
| A | HOH6022 |
| A | HOH6171 |
| A | HOH6215 |
| B | TYR1032 |
| B | THR1036 |
| B | TYR1144 |
| B | LEU1153 |
| B | ASP1177 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00193","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FYD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IH8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00193","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1FYD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IH8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"HAMAP-Rule","id":"MF_00193","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00193","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NSY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00193","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"1EE1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IFX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2NSY","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
