1IFX
CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH TWO MOLECULES DEAMIDO-NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008795 | molecular_function | NAD+ synthase activity |
| A | 0009435 | biological_process | NAD biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0030435 | biological_process | sporulation resulting in formation of a cellular spore |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003952 | molecular_function | NAD+ synthase (glutamine-hydrolyzing) activity |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008795 | molecular_function | NAD+ synthase activity |
| B | 0009435 | biological_process | NAD biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0030435 | biological_process | sporulation resulting in formation of a cellular spore |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DND B 7000 |
| Chain | Residue |
| A | TYR32 |
| B | PHE1168 |
| B | THR1169 |
| B | LYS1170 |
| B | ASP1173 |
| B | HIS1257 |
| B | LYS1258 |
| B | HOH6091 |
| B | HOH6181 |
| B | HOH6214 |
| A | THR36 |
| A | TYR144 |
| A | LEU153 |
| A | ASP177 |
| B | PHE1129 |
| B | ASN1133 |
| B | ARG1137 |
| B | PHE1167 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DND A 8000 |
| Chain | Residue |
| A | PHE129 |
| A | ASN133 |
| A | ARG137 |
| A | PHE167 |
| A | PHE168 |
| A | THR169 |
| A | LYS170 |
| A | HIS257 |
| A | LYS258 |
| A | HOH6022 |
| A | HOH6171 |
| A | HOH6215 |
| B | TYR1032 |
| B | THR1036 |
| B | TYR1144 |
| B | LEU1153 |
| B | ASP1177 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | VAL33 | |
| B | VAL1033 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | ILE45 | |
| A | ARG187 | |
| B | ILE1045 | |
| B | ARG1187 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | SER51 | |
| A | ALA163 | |
| B | SER1051 | |
| B | ALA1163 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | LEU79 | |
| A | GLN85 | |
| B | LEU1079 | |
| B | GLN1085 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: in other chain => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | THR138 | |
| A | TYR171 | |
| A | LYS258 | |
| B | THR1138 | |
| B | TYR1171 | |
| B | LYS1258 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | ASP158 | |
| B | ASP1158 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1IFX, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | LEU178 | |
| B | LEU1178 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00193, ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1FYD, ECO:0007744|PDB:1IH8, ECO:0007744|PDB:1NSY, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | ALA209 | |
| B | ALA1209 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | BINDING: in other chain => ECO:0007744|PDB:1EE1, ECO:0007744|PDB:1KQP, ECO:0007744|PDB:2NSY |
| Chain | Residue | Details |
| A | LEU224 | |
| B | LEU1224 |
