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1IF1

INTERFERON REGULATORY FACTOR 1 (IRF-1) COMPLEX WITH DNA

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
B0000976molecular_functiontranscription cis-regulatory region binding
B0003700molecular_functionDNA-binding transcription factor activity
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WiNkeemiFqIPWkHaakhgwdinkDacLFRsWA
ChainResidueDetails
ATRP26-ALA59

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues216
DetailsDNA_BIND: IRF tryptophan pentad repeat => ECO:0000255|PROSITE-ProRule:PRU00840
ChainResidueDetails
ATRP5-PRO113
BTRP5-PRO113

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P10914
ChainResidueDetails
ALYS78
BLYS78

227111

PDB entries from 2024-11-06

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