1IE6

SOLUTION STRUCTURE OF IMPERATOXIN A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0019855	molecular_function	calcium channel inhibitor activity

Functional Information from PROSITE/UniProt

site_id	PS60028
Number of Residues	30
Details	SCORPION_CALCINE Scorpion calcine family signature. ClphlkrCkadndCCgkkCkrrgtnaekRC

Chain	Residue	Details
A	CYS3-CYS32

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Peptide: {"description":"Imperacalcin","featureId":"PRO_0000044949","evidences":[{"source":"PubMed","id":"9108323","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Region: {"description":"Important for stimulation of [3H]ryanodine binding to RYR1","evidences":[{"source":"PubMed","id":"14535845","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Region: {"description":"Essential for stimulation of [3H]ryanodine binding to RYR1","evidences":[{"source":"PubMed","id":"14535845","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	3
Details	Site: {"description":"Important for stimulation of [3H]ryanodine binding to RYR1","evidences":[{"source":"PubMed","id":"14535845","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	3
Details	Site: {"description":"Essential for stimulation of [3H]ryanodine binding to RYR1","evidences":[{"source":"PubMed","id":"14535845","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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