1IDS
X-RAY STRUCTURE ANALYSIS OF THE IRON-DEPENDENT SUPEROXIDE DISMUTASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.0 ANGSTROMS RESOLUTIONS REVEALS NOVEL DIMER-DIMER INTERACTIONS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004784 | molecular_function | superoxide dismutase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006801 | biological_process | superoxide metabolic process |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098754 | biological_process | detoxification |
| B | 0004784 | molecular_function | superoxide dismutase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006801 | biological_process | superoxide metabolic process |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098754 | biological_process | detoxification |
| C | 0004784 | molecular_function | superoxide dismutase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006801 | biological_process | superoxide metabolic process |
| C | 0006979 | biological_process | response to oxidative stress |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019430 | biological_process | removal of superoxide radicals |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0098754 | biological_process | detoxification |
| D | 0004784 | molecular_function | superoxide dismutase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0005515 | molecular_function | protein binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005829 | cellular_component | cytosol |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006801 | biological_process | superoxide metabolic process |
| D | 0006979 | biological_process | response to oxidative stress |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019430 | biological_process | removal of superoxide radicals |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0098754 | biological_process | detoxification |
Functional Information from PDB Data
| site_id | A1 |
| Number of Residues | 1 |
| Details | CATALYTIC SITE OF CHAIN A |
| Chain | Residue |
| A | FE208 |
| site_id | A2 |
| Number of Residues | 1 |
| Details | CATALYTIC SITE OF CHAIN B |
| Chain | Residue |
| B | FE208 |
| site_id | A3 |
| Number of Residues | 1 |
| Details | CATALYTIC SITE OF CHAIN C |
| Chain | Residue |
| C | FE208 |
| site_id | A4 |
| Number of Residues | 1 |
| Details | CATALYTIC SITE OF CHAIN D |
| Chain | Residue |
| D | FE208 |
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 208 |
| Chain | Residue |
| A | HIS28 |
| A | HIS76 |
| A | ASP160 |
| A | HIS164 |
| A | HOH1001 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 208 |
| Chain | Residue |
| B | HIS28 |
| B | HIS76 |
| B | ASP160 |
| B | HIS164 |
| B | HOH1002 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE C 208 |
| Chain | Residue |
| C | HIS28 |
| C | HIS76 |
| C | ASP160 |
| C | HIS164 |
| C | HOH1003 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE D 208 |
| Chain | Residue |
| D | HIS28 |
| D | HIS76 |
| D | ASP160 |
| D | HIS164 |
| D | HOH1004 |
Functional Information from PROSITE/UniProt
| site_id | PS00088 |
| Number of Residues | 8 |
| Details | SOD_MN Manganese and iron superoxide dismutases signature. DmWEHAFY |
| Chain | Residue | Details |
| A | ASP160-TYR167 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11747311","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"7877174","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8674528","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9490054","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1GN2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GN3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1GN6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1IDS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
