Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051287 | molecular_function | NAD binding |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NIFGDIlSDlaSvlp.GSLGL |
| Chain | Residue | Details |
| A | ASN235-LEU254 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLY74 | |
| A | PRO275 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 13 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER94 | |
| A | THR133 | |
| A | ALA218 | |
| A | SER242 | |
| A | SER246 | |
| A | ALA104 | |
| A | LEU132 | |
| A | MET217 | |
| A | LEU241 | |
| A | ALA245 | |
| A | ALA274 | |
| A | GLN95 | |
| A | LYS105 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | SITE: Important for catalysis => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY139 | |
| A | ASN185 | |
| A | VAL186 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Important for catalysis |
| Chain | Residue | Details |
| A | GLU140 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | TYR137 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | ASP215 | |
| A | LYS183 | |
