Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 280 |
| Chain | Residue |
| A | PRO175 |
| A | VAL177 |
| A | ASP200 |
| A | HOH301 |
| A | HOH303 |
| A | HOH304 |
| A | HOH729 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 281 |
| Chain | Residue |
| A | HOH305 |
| A | HOH589 |
| A | HOH730 |
| A | THR16 |
| A | ASP260 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 A 901 |
| Chain | Residue |
| A | TYR60 |
| A | TYR61 |
| A | ARG80 |
| A | LYS94 |
| A | ASP97 |
| A | ASP98 |
| A | HOH343 |
| A | HOH631 |
| A | HOH789 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 A 902 |
| Chain | Residue |
| A | ALA158 |
| A | GLY160 |
| A | ASN161 |
| A | THR223 |
| A | SER224 |
| A | HOH468 |
| A | HOH480 |
| A | HOH483 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 A 903 |
| Chain | Residue |
| A | GLY102 |
| A | TYR104 |
| A | ILE107 |
| A | LEU133 |
| A | GLY134 |
| A | HOH455 |
| A | HOH456 |
| A | HOH485 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 904 |
| Chain | Residue |
| A | ARG64 |
| A | ASP165 |
| A | ARG167 |
| A | ASN168 |
| A | ILE213 |
| A | GLY214 |
| A | HOH545 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NO3 A 905 |
| Chain | Residue |
| A | ILE220 |
| A | HOH401 |
| A | HOH482 |
| A | HOH491 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 A 906 |
| Chain | Residue |
| A | ASP184 |
| A | TYR186 |
| A | ARG188 |
| A | THR244 |
| A | HOH428 |
| A | HOH713 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 A 907 |
| Chain | Residue |
| A | TYR104 |
| A | SER105 |
| A | ILE108 |
| A | SER140 |
| A | HOH338 |
| A | HOH656 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 908 |
| Chain | Residue |
| A | SER191 |
| A | ALA246 |
| A | SER247 |
| A | ARG250 |
| A | HOH479 |
| A | HOH654 |
| A | HOH733 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VYVIDTGIeasH |
| Chain | Residue | Details |
| A | VAL35-HIS46 | |
| site_id | PS00137 |
| Number of Residues | 11 |
| Details | SUBTILASE_HIS Serine proteases, subtilase family, histidine active site. HGThCAGtVGS |
| Chain | Residue | Details |
| A | HIS69-SER79 | |
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSmAtPhVAG |
| Chain | Residue | Details |
| A | GLY222-GLY232 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 272 |
| Details | Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1sca |
| Chain | Residue | Details |
| A | SER224 | |
| A | ASP39 | |
| A | HIS69 | |
