Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TIIHELMHAI |
Chain | Residue | Details |
A | THR89-ILE98 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU93 | |
Chain | Residue | Details |
A | HIS92 | |
A | HIS96 | |
A | HIS102 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1ast |
Chain | Residue | Details |
A | TYR149 | |
A | GLU93 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 403 |
Chain | Residue | Details |
A | HIS92 | metal ligand |
A | GLU93 | proton shuttle (general acid/base) |
A | HIS96 | metal ligand |
A | HIS102 | metal ligand |
A | TYR149 | transition state stabiliser |