1I7K

CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN-CONJUGATING ENZYME, UBCH10

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000151	cellular_component	ubiquitin ligase complex
A	0000166	molecular_function	nucleotide binding
A	0000209	biological_process	protein polyubiquitination
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005680	cellular_component	anaphase-promoting complex
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0010458	biological_process	exit from mitosis
A	0010994	biological_process	free ubiquitin chain polymerization
A	0016567	biological_process	protein ubiquitination
A	0016740	molecular_function	transferase activity
A	0019787	molecular_function	ubiquitin-like protein transferase activity
A	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
A	0031145	biological_process	anaphase-promoting complex-dependent catabolic process
A	0031536	biological_process	positive regulation of exit from mitosis
A	0032446	biological_process	protein modification by small protein conjugation
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0044389	molecular_function	ubiquitin-like protein ligase binding
A	0045842	biological_process	positive regulation of mitotic metaphase/anaphase transition
A	0051301	biological_process	cell division
A	0061630	molecular_function	ubiquitin protein ligase activity
A	0061631	molecular_function	ubiquitin conjugating enzyme activity
A	0070936	biological_process	protein K48-linked ubiquitination
A	0070979	biological_process	protein K11-linked ubiquitination
A	1904668	biological_process	positive regulation of ubiquitin protein ligase activity
B	0000151	cellular_component	ubiquitin ligase complex
B	0000166	molecular_function	nucleotide binding
B	0000209	biological_process	protein polyubiquitination
B	0004842	molecular_function	ubiquitin-protein transferase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005680	cellular_component	anaphase-promoting complex
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006511	biological_process	ubiquitin-dependent protein catabolic process
B	0010458	biological_process	exit from mitosis
B	0010994	biological_process	free ubiquitin chain polymerization
B	0016567	biological_process	protein ubiquitination
B	0016740	molecular_function	transferase activity
B	0019787	molecular_function	ubiquitin-like protein transferase activity
B	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
B	0031145	biological_process	anaphase-promoting complex-dependent catabolic process
B	0031536	biological_process	positive regulation of exit from mitosis
B	0032446	biological_process	protein modification by small protein conjugation
B	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
B	0044389	molecular_function	ubiquitin-like protein ligase binding
B	0045842	biological_process	positive regulation of mitotic metaphase/anaphase transition
B	0051301	biological_process	cell division
B	0061630	molecular_function	ubiquitin protein ligase activity
B	0061631	molecular_function	ubiquitin conjugating enzyme activity
B	0070936	biological_process	protein K48-linked ubiquitination
B	0070979	biological_process	protein K11-linked ubiquitination
B	1904668	biological_process	positive regulation of ubiquitin protein ligase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	290
Details	Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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