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1I7K

CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN-CONJUGATING ENZYME, UBCH10

Functional Information from GO Data
ChainGOidnamespacecontents
A0000151cellular_componentubiquitin ligase complex
A0000209biological_processprotein polyubiquitination
A0004842molecular_functionubiquitin-protein transferase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005680cellular_componentanaphase-promoting complex
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006511biological_processubiquitin-dependent protein catabolic process
A0010458biological_processexit from mitosis
A0010994biological_processfree ubiquitin chain polymerization
A0016567biological_processprotein ubiquitination
A0016740molecular_functiontransferase activity
A0019787molecular_functionubiquitin-like protein transferase activity
A0030071biological_processregulation of mitotic metaphase/anaphase transition
A0031145biological_processanaphase-promoting complex-dependent catabolic process
A0031536biological_processpositive regulation of exit from mitosis
A0032446biological_processprotein modification by small protein conjugation
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0044389molecular_functionubiquitin-like protein ligase binding
A0045842biological_processpositive regulation of mitotic metaphase/anaphase transition
A0051301biological_processcell division
A0061630molecular_functionubiquitin protein ligase activity
A0061631molecular_functionubiquitin conjugating enzyme activity
A0070936biological_processprotein K48-linked ubiquitination
A0070979biological_processprotein K11-linked ubiquitination
A1904668biological_processpositive regulation of ubiquitin protein ligase activity
B0000151cellular_componentubiquitin ligase complex
B0000209biological_processprotein polyubiquitination
B0004842molecular_functionubiquitin-protein transferase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005680cellular_componentanaphase-promoting complex
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006511biological_processubiquitin-dependent protein catabolic process
B0010458biological_processexit from mitosis
B0010994biological_processfree ubiquitin chain polymerization
B0016567biological_processprotein ubiquitination
B0016740molecular_functiontransferase activity
B0019787molecular_functionubiquitin-like protein transferase activity
B0030071biological_processregulation of mitotic metaphase/anaphase transition
B0031145biological_processanaphase-promoting complex-dependent catabolic process
B0031536biological_processpositive regulation of exit from mitosis
B0032446biological_processprotein modification by small protein conjugation
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0044389molecular_functionubiquitin-like protein ligase binding
B0045842biological_processpositive regulation of mitotic metaphase/anaphase transition
B0051301biological_processcell division
B0061630molecular_functionubiquitin protein ligase activity
B0061631molecular_functionubiquitin conjugating enzyme activity
B0070936biological_processprotein K48-linked ubiquitination
B0070979biological_processprotein K11-linked ubiquitination
B1904668biological_processpositive regulation of ubiquitin protein ligase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
ChainResidueDetails
ASER114
BSER114

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylalanine => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:21406692
ChainResidueDetails
AALA2
BALA2

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
ASER3
BSER3

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PDB entries from 2024-07-10

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