Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004014 | molecular_function | adenosylmethionine decarboxylase activity |
| A | 0006597 | biological_process | spermine biosynthetic process |
| A | 0008295 | biological_process | spermidine biosynthetic process |
| B | 0004014 | molecular_function | adenosylmethionine decarboxylase activity |
| B | 0008295 | biological_process | spermidine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SMM A 368 |
| Chain | Residue |
| A | PYR68 |
| A | TYR228 |
| A | SER229 |
| A | ILE244 |
| A | THR245 |
| A | PRO246 |
| A | GLU247 |
| A | HOH563 |
| B | PHE7 |
| B | LEU65 |
| B | SER66 |
| A | SER69 |
| B | GLU67 |
| A | THR81 |
| A | CYS82 |
| A | THR85 |
| A | PHE223 |
| A | ASN224 |
| A | CYS226 |
| A | GLY227 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PUT A 350 |
| Chain | Residue |
| A | PHE111 |
| A | ASP174 |
| A | THR176 |
| A | PHE285 |
| A | TYR318 |
| A | HOH401 |
| A | HOH404 |
| A | HOH507 |
| B | LEU13 |
| B | GLU15 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"1917972","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11583147","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor; for catalytic activity","evidences":[{"source":"PubMed","id":"10029540","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11583147","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; for processing activity","evidences":[{"source":"PubMed","id":"11583147","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1jen |
| Chain | Residue | Details |
| A | HIS243 | |
| A | SER229 | |
| A | CYS82 | |
| B | GLU11 | |
| B | GLU67 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 575 |
| Chain | Residue | Details |
| B | SER19 | proton shuttle (general acid/base) |
