1I4N

CRYSTAL STRUCTURE OF INDOLEGLYCEROL PHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000162	biological_process	tryptophan biosynthetic process
A	0004425	molecular_function	indole-3-glycerol-phosphate synthase activity
A	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
A	0006568	biological_process	tryptophan metabolic process
A	0006586	biological_process	indolalkylamine metabolic process
A	0009072	biological_process	aromatic amino acid metabolic process
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	1901605	biological_process	alpha-amino acid metabolic process
B	0000162	biological_process	tryptophan biosynthetic process
B	0004425	molecular_function	indole-3-glycerol-phosphate synthase activity
B	0004640	molecular_function	phosphoribosylanthranilate isomerase activity
B	0006568	biological_process	tryptophan metabolic process
B	0006586	biological_process	indolalkylamine metabolic process
B	0009072	biological_process	aromatic amino acid metabolic process
B	0016830	molecular_function	carbon-carbon lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	1901605	biological_process	alpha-amino acid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 500

Chain	Residue
A	LYS49
A	ARG181
A	SER210
A	GLY211
A	GLY231
A	THR232
A	HOH618
A	HOH619

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 501

Chain	Residue
B	ARG181
B	SER210
B	GLY231
B	THR232
B	HOH643
B	HOH644
B	LYS49

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Functional Information from PROSITE/UniProt

site_id	PS00614
Number of Residues	15
Details	IGPS Indole-3-glycerol phosphate synthase signature. IIaEFKKASPSagd....I

Chain	Residue	Details
A	ILE44-ILE58

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1pii

Chain	Residue	Details
A	ASN179
A	GLU47
A	LYS49
A	SER210
A	GLU157
A	LYS108

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site_id	CSA2
Number of Residues	6
Details	Annotated By Reference To The Literature 1pii

Chain	Residue	Details
B	ASN179
B	GLU47
B	LYS49
B	SER210
B	GLU157
B	LYS108

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