1I4N
CRYSTAL STRUCTURE OF INDOLEGLYCEROL PHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| A | 0006568 | biological_process | L-tryptophan metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0000162 | biological_process | L-tryptophan biosynthetic process |
| B | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| B | 0006568 | biological_process | L-tryptophan metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 500 |
| Chain | Residue |
| A | LYS49 |
| A | ARG181 |
| A | SER210 |
| A | GLY211 |
| A | GLY231 |
| A | THR232 |
| A | HOH618 |
| A | HOH619 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| B | ARG181 |
| B | SER210 |
| B | GLY231 |
| B | THR232 |
| B | HOH643 |
| B | HOH644 |
| B | LYS49 |
Functional Information from PROSITE/UniProt
| site_id | PS00614 |
| Number of Residues | 15 |
| Details | IGPS Indole-3-glycerol phosphate synthase signature. IIaEFKKASPSagd....I |
| Chain | Residue | Details |
| A | ILE44-ILE58 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1pii |
| Chain | Residue | Details |
| A | ASN179 | |
| A | GLU47 | |
| A | LYS49 | |
| A | SER210 | |
| A | GLU157 | |
| A | LYS108 |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1pii |
| Chain | Residue | Details |
| B | ASN179 | |
| B | GLU47 | |
| B | LYS49 | |
| B | SER210 | |
| B | GLU157 | |
| B | LYS108 |
