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1I4G

Crystal structure of Staphylococcal enterotoxin A mutant H187A with reduced Zn2+ affinity

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0035821biological_processmodulation of process of another organism
A0042289molecular_functionMHC class II protein binding
A0046872molecular_functionmetal ion binding
A0090729molecular_functiontoxin activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0035821biological_processmodulation of process of another organism
B0042289molecular_functionMHC class II protein binding
B0046872molecular_functionmetal ion binding
B0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 460
ChainResidue
AHIS44
AHIS225
AASP227
AHOH507

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 B 1000
ChainResidue
BHOH1084
BTYR92
BGLY93
BTYR94
BSER206
BHOH1083

Functional Information from PROSITE/UniProt
site_idPS00277
Number of Residues10
DetailsSTAPH_STREP_TOXIN_1 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. YGGVTLHdnN
ChainResidueDetails
ATYR108-ASN117

site_idPS00278
Number of Residues24
DetailsSTAPH_STREP_TOXIN_2 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. KknVtvqeLDlqaRryLqekynLY
ChainResidueDetails
ALYS147-TYR170

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:11847286, ECO:0007744|PDB:1DYQ
ChainResidueDetails
AALA187
BALA187

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:11713682, ECO:0000269|PubMed:11847286, ECO:0007744|PDB:1DYQ, ECO:0007744|PDB:1I4G, ECO:0007744|PDB:1I4H
ChainResidueDetails
AHIS225
AASP227
BHIS225
BASP227

222624

PDB entries from 2024-07-17

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