1I37
CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN COMPLEX WITH DIHYDROTESTOSTERONE
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DHT A 201 |
| Chain | Residue |
| A | LEU704 |
| A | THR877 |
| A | PHE891 |
| A | ASN705 |
| A | GLN711 |
| A | MET745 |
| A | MET749 |
| A | ARG752 |
| A | PHE764 |
| A | MET787 |
| A | PHE876 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11320241, ECO:0007744|PDB:1I37 |
| Chain | Residue | Details |
| A | ASN705 | |
| A | ARG752 | |
| A | THR877 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Interaction with coactivator LXXL and FXXFY motifs => ECO:0000250|UniProtKB:P10275 |
| Chain | Residue | Details |
| A | LYS720 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Interaction with coactivator FXXLF and FXXFY motifs => ECO:0000250|UniProtKB:P10275 |
| Chain | Residue | Details |
| A | GLU897 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by CSK => ECO:0000250|UniProtKB:P10275 |
| Chain | Residue | Details |
| A | TYR915 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P10275 |
| Chain | Residue | Details |
| A | LYS845 | |
| A | LYS847 |
