1HXH
COMAMONAS TESTOSTERONI 3BETA/17BETA HYDROXYSTEROID DEHYDROGENASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030283 | molecular_function | testosterone dehydrogenase [NAD(P)+] activity |
| A | 0035410 | molecular_function | dihydrotestosterone 17-beta-dehydrogenase activity |
| A | 0047035 | molecular_function | testosterone dehydrogenase (NAD+) activity |
| A | 0047045 | molecular_function | testosterone 17-beta-dehydrogenase (NADP+) activity |
| B | 0008202 | biological_process | steroid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0030283 | molecular_function | testosterone dehydrogenase [NAD(P)+] activity |
| B | 0035410 | molecular_function | dihydrotestosterone 17-beta-dehydrogenase activity |
| B | 0047035 | molecular_function | testosterone dehydrogenase (NAD+) activity |
| B | 0047045 | molecular_function | testosterone 17-beta-dehydrogenase (NADP+) activity |
| C | 0008202 | biological_process | steroid metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0030283 | molecular_function | testosterone dehydrogenase [NAD(P)+] activity |
| C | 0035410 | molecular_function | dihydrotestosterone 17-beta-dehydrogenase activity |
| C | 0047035 | molecular_function | testosterone dehydrogenase (NAD+) activity |
| C | 0047045 | molecular_function | testosterone 17-beta-dehydrogenase (NADP+) activity |
| D | 0008202 | biological_process | steroid metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0030283 | molecular_function | testosterone dehydrogenase [NAD(P)+] activity |
| D | 0035410 | molecular_function | dihydrotestosterone 17-beta-dehydrogenase activity |
| D | 0047035 | molecular_function | testosterone dehydrogenase (NAD+) activity |
| D | 0047045 | molecular_function | testosterone 17-beta-dehydrogenase (NADP+) activity |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvsswlpieqYagYSASKAAVsALTrAAA |
| Chain | Residue | Details |
| A | SER138-ALA166 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001 |
| Chain | Residue | Details |
| A | TYR151 | |
| B | TYR151 | |
| C | TYR151 | |
| D | TYR151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | VAL11 | |
| C | ASP60 | |
| C | SER138 | |
| C | LYS155 | |
| D | VAL11 | |
| D | ASP60 | |
| D | SER138 | |
| D | LYS155 | |
| A | ASP60 | |
| A | SER138 | |
| A | LYS155 | |
| B | VAL11 | |
| B | ASP60 | |
| B | SER138 | |
| B | LYS155 | |
| C | VAL11 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | LYS155 | |
| A | SER138 | |
| A | TYR151 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | LYS155 | |
| C | TYR148 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | LYS155 | |
| D | TYR148 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | LYS155 | |
| A | TYR151 |
| site_id | CSA13 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS155 | |
| B | TYR151 |
| site_id | CSA14 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | LYS155 | |
| C | TYR151 |
| site_id | CSA15 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | LYS155 | |
| D | TYR151 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS155 | |
| B | SER138 | |
| B | TYR151 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | LYS155 | |
| C | SER138 | |
| C | TYR151 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | ASN111 | |
| A | LYS155 | |
| A | SER138 | |
| A | TYR151 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | ASN111 | |
| B | LYS155 | |
| B | SER138 | |
| B | TYR151 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| C | ASN111 | |
| C | LYS155 | |
| C | SER138 | |
| C | TYR151 |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| D | ASN111 | |
| D | LYS155 | |
| D | SER138 | |
| D | TYR151 |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| A | LYS155 | |
| A | TYR148 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1eq2 |
| Chain | Residue | Details |
| B | LYS155 | |
| B | TYR148 |
