1HXH

COMAMONAS TESTOSTERONI 3BETA/17BETA HYDROXYSTEROID DEHYDROGENASE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process
A	0008202	biological_process	steroid metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0030283	molecular_function	testosterone dehydrogenase [NAD(P)] activity
A	0035410	molecular_function	dihydrotestosterone 17-beta-dehydrogenase activity
A	0047035	molecular_function	testosterone dehydrogenase (NAD+) activity
A	0047045	molecular_function	testosterone 17-beta-dehydrogenase (NADP+) activity
B	0006629	biological_process	lipid metabolic process
B	0008202	biological_process	steroid metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0030283	molecular_function	testosterone dehydrogenase [NAD(P)] activity
B	0035410	molecular_function	dihydrotestosterone 17-beta-dehydrogenase activity
B	0047035	molecular_function	testosterone dehydrogenase (NAD+) activity
B	0047045	molecular_function	testosterone 17-beta-dehydrogenase (NADP+) activity
C	0006629	biological_process	lipid metabolic process
C	0008202	biological_process	steroid metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0030283	molecular_function	testosterone dehydrogenase [NAD(P)] activity
C	0035410	molecular_function	dihydrotestosterone 17-beta-dehydrogenase activity
C	0047035	molecular_function	testosterone dehydrogenase (NAD+) activity
C	0047045	molecular_function	testosterone 17-beta-dehydrogenase (NADP+) activity
D	0006629	biological_process	lipid metabolic process
D	0008202	biological_process	steroid metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0030283	molecular_function	testosterone dehydrogenase [NAD(P)] activity
D	0035410	molecular_function	dihydrotestosterone 17-beta-dehydrogenase activity
D	0047035	molecular_function	testosterone dehydrogenase (NAD+) activity
D	0047045	molecular_function	testosterone 17-beta-dehydrogenase (NADP+) activity

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvsswlpieqYagYSASKAAVsALTrAAA

Chain	Residue	Details
A	SER138-ALA166

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001

Chain	Residue	Details
A	TYR151
B	TYR151
C	TYR151
D	TYR151

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site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	VAL11
C	ASP60
C	SER138
C	LYS155
D	VAL11
D	ASP60
D	SER138
D	LYS155
A	ASP60
A	SER138
A	LYS155
B	VAL11
B	ASP60
B	SER138
B	LYS155
C	VAL11

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