1HXC
CRYSTAL STRUCTURE OF TEAS C440W
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000287 | molecular_function | magnesium ion binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006720 | biological_process | isoprenoid metabolic process |
A | 0010333 | molecular_function | terpene synthase activity |
A | 0016102 | biological_process | diterpenoid biosynthetic process |
A | 0016114 | biological_process | terpenoid biosynthetic process |
A | 0016829 | molecular_function | lyase activity |
A | 0016838 | molecular_function | carbon-oxygen lyase activity, acting on phosphates |
A | 0046872 | molecular_function | metal ion binding |
A | 0051762 | biological_process | sesquiterpene biosynthetic process |
A | 0102698 | molecular_function | 5-epi-aristolochene synthase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE FHP A 900 |
Chain | Residue |
A | ARG266 |
A | THR403 |
A | CYS270 |
A | ILE294 |
A | ASP301 |
A | ASP305 |
A | TYR376 |
A | GLU379 |
A | THR401 |
A | THR402 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:27328867, ECO:0000305|PubMed:25897591, ECO:0000305|PubMed:9295271, ECO:0000305|Ref.13, ECO:0000305|Ref.9, ECO:0007744|PDB:3LZ9, ECO:0007744|PDB:3M00, ECO:0007744|PDB:3M01, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4DI5, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5EAU, ECO:0007744|PDB:5IK0, ECO:0007744|PDB:5IK6, ECO:0007744|PDB:5IK9, ECO:0007744|PDB:5IKA, ECO:0007744|PDB:5IKH, ECO:0007744|PDB:5IL8, ECO:0007744|PDB:5ILD, ECO:0007744|PDB:5ILY |
Chain | Residue | Details |
A | ARG264 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:25897591, ECO:0000269|PubMed:26378620, ECO:0000269|PubMed:27328867, ECO:0000269|PubMed:9295271, ECO:0007744|PDB:3LZ9, ECO:0007744|PDB:3M00, ECO:0007744|PDB:3M01, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5DHI, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5IK0, ECO:0007744|PDB:5IK9, ECO:0007744|PDB:5IKA |
Chain | Residue | Details |
A | ASP301 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:25897591, ECO:0000269|PubMed:26378620, ECO:0000269|PubMed:27328867, ECO:0000269|PubMed:9295271, ECO:0007744|PDB:1HXA, ECO:0007744|PDB:3LZ9, ECO:0007744|PDB:3M00, ECO:0007744|PDB:3M01, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5DHI, ECO:0007744|PDB:5DHK, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5IK0, ECO:0007744|PDB:5IK9, ECO:0007744|PDB:5IKA |
Chain | Residue | Details |
A | ASP305 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:27328867, ECO:0000305|PubMed:20175559, ECO:0000305|PubMed:25897591, ECO:0000305|PubMed:27328867, ECO:0000305|Ref.13, ECO:0000305|Ref.7, ECO:0000305|Ref.9, ECO:0007744|PDB:1HXA, ECO:0007744|PDB:1HXC, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4DI5, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5IK0, ECO:0007744|PDB:5IK6, ECO:0007744|PDB:5IKA, ECO:0007744|PDB:5IL3, ECO:0007744|PDB:5ILH, ECO:0007744|PDB:5ILI, ECO:0007744|PDB:5ILY |
Chain | Residue | Details |
A | ARG441 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:25897591, ECO:0000269|PubMed:26378620, ECO:0000269|PubMed:27328867, ECO:0000269|PubMed:9295271, ECO:0000269|Ref.13, ECO:0000269|Ref.7, ECO:0000269|Ref.9, ECO:0007744|PDB:1HX9, ECO:0007744|PDB:1HXA, ECO:0007744|PDB:3LZ9, ECO:0007744|PDB:3M00, ECO:0007744|PDB:3M01, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4DI5, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5DHI, ECO:0007744|PDB:5EAS, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5EAU, ECO:0007744|PDB:5IK0, ECO:0007744|PDB:5IK6, ECO:0007744|PDB:5IK9, ECO:0007744|PDB:5IKA, ECO:0007744|PDB:5IKH, ECO:0007744|PDB:5IL3, ECO:0007744|PDB:5ILD, ECO:0007744|PDB:5ILI, ECO:0007744|PDB:5ILY |
Chain | Residue | Details |
A | ASP444 | |
A | GLU452 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:25897591, ECO:0000269|PubMed:27328867, ECO:0000269|PubMed:9295271, ECO:0000269|Ref.13, ECO:0000269|Ref.9, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4DI5, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5EAS, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5IKH, ECO:0007744|PDB:5ILD |
Chain | Residue | Details |
A | ASP445 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | BINDING: BINDING => ECO:0000269|PubMed:20175559, ECO:0000269|PubMed:25897591, ECO:0000269|PubMed:26378620, ECO:0000269|PubMed:27328867, ECO:0000269|PubMed:9295271, ECO:0000269|Ref.13, ECO:0000269|Ref.7, ECO:0000269|Ref.9, ECO:0007744|PDB:1HX9, ECO:0007744|PDB:1HXA, ECO:0007744|PDB:3LZ9, ECO:0007744|PDB:3M00, ECO:0007744|PDB:3M01, ECO:0007744|PDB:3M02, ECO:0007744|PDB:4DI5, ECO:0007744|PDB:4RNQ, ECO:0007744|PDB:5DHI, ECO:0007744|PDB:5EAS, ECO:0007744|PDB:5EAT, ECO:0007744|PDB:5EAU, ECO:0007744|PDB:5IK9, ECO:0007744|PDB:5IKA, ECO:0007744|PDB:5IKH, ECO:0007744|PDB:5ILD, ECO:0007744|PDB:5ILI, ECO:0007744|PDB:5ILY |
Chain | Residue | Details |
A | THR448 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1n20 |
Chain | Residue | Details |
A | TRP273 |
site_id | CSA2 |
Number of Residues | 8 |
Details | Annotated By Reference To The Literature 1n20 |
Chain | Residue | Details |
A | ARG441 | |
A | THR401 | |
A | THR403 | |
A | TRP273 | |
A | ARG264 | |
A | ASP444 | |
A | TYR520 | |
A | THR402 |
site_id | MCSA1 |
Number of Residues | 10 |
Details | M-CSA 265 |
Chain | Residue | Details |
A | ARG264 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
A | TYR527 | electrostatic stabiliser, polar interaction |
A | TRP273 | electrostatic stabiliser, hydrogen bond donor, polar interaction, proton acceptor, proton donor |
A | THR401 | electrostatic stabiliser, polar interaction |
A | THR402 | electrostatic stabiliser, polar interaction |
A | THR403 | electrostatic stabiliser, polar interaction |
A | ARG441 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
A | ASP444 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | TYR520 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
A | ASP525 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |