1HV4

CRYSTAL STRUCTURE ANALYSIS OF BAR-HEAD GOOSE HEMOGLOBIN (DEOXY FORM)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0043177	molecular_function	organic acid binding
A	0046872	molecular_function	metal ion binding
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0031720	molecular_function	haptoglobin binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0043177	molecular_function	organic acid binding
B	0046872	molecular_function	metal ion binding
B	0072562	cellular_component	blood microparticle
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031720	molecular_function	haptoglobin binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0043177	molecular_function	organic acid binding
C	0046872	molecular_function	metal ion binding
C	0072562	cellular_component	blood microparticle
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005344	molecular_function	oxygen carrier activity
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0031720	molecular_function	haptoglobin binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0043177	molecular_function	organic acid binding
D	0046872	molecular_function	metal ion binding
D	0072562	cellular_component	blood microparticle
D	0098869	biological_process	cellular oxidant detoxification
E	0004601	molecular_function	peroxidase activity
E	0005344	molecular_function	oxygen carrier activity
E	0005506	molecular_function	iron ion binding
E	0005833	cellular_component	hemoglobin complex
E	0015671	biological_process	oxygen transport
E	0019825	molecular_function	oxygen binding
E	0020037	molecular_function	heme binding
E	0031720	molecular_function	haptoglobin binding
E	0031838	cellular_component	haptoglobin-hemoglobin complex
E	0042744	biological_process	hydrogen peroxide catabolic process
E	0043177	molecular_function	organic acid binding
E	0046872	molecular_function	metal ion binding
E	0072562	cellular_component	blood microparticle
E	0098869	biological_process	cellular oxidant detoxification
F	0004601	molecular_function	peroxidase activity
F	0005344	molecular_function	oxygen carrier activity
F	0005833	cellular_component	hemoglobin complex
F	0015671	biological_process	oxygen transport
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
F	0031720	molecular_function	haptoglobin binding
F	0031838	cellular_component	haptoglobin-hemoglobin complex
F	0042744	biological_process	hydrogen peroxide catabolic process
F	0043177	molecular_function	organic acid binding
F	0046872	molecular_function	metal ion binding
F	0072562	cellular_component	blood microparticle
F	0098869	biological_process	cellular oxidant detoxification
G	0004601	molecular_function	peroxidase activity
G	0005344	molecular_function	oxygen carrier activity
G	0005506	molecular_function	iron ion binding
G	0005833	cellular_component	hemoglobin complex
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0031720	molecular_function	haptoglobin binding
G	0031838	cellular_component	haptoglobin-hemoglobin complex
G	0042744	biological_process	hydrogen peroxide catabolic process
G	0043177	molecular_function	organic acid binding
G	0046872	molecular_function	metal ion binding
G	0072562	cellular_component	blood microparticle
G	0098869	biological_process	cellular oxidant detoxification
H	0004601	molecular_function	peroxidase activity
H	0005344	molecular_function	oxygen carrier activity
H	0005833	cellular_component	hemoglobin complex
H	0015671	biological_process	oxygen transport
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding
H	0031720	molecular_function	haptoglobin binding
H	0031838	cellular_component	haptoglobin-hemoglobin complex
H	0042744	biological_process	hydrogen peroxide catabolic process
H	0043177	molecular_function	organic acid binding
H	0046872	molecular_function	metal ion binding
H	0072562	cellular_component	blood microparticle
H	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM A 151

Chain	Residue
A	TYR42
A	LEU101
A	VAL132
A	PHE43
A	HIS45
A	PHE46
A	HIS58
A	LYS61
A	HIS87
A	ASN97
A	PHE98

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE HEM B 152

Chain	Residue
B	PHE41
B	PHE42
B	HIS63
B	LYS66
B	SER70
B	HIS92
B	ASN102
B	LEU141

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM C 153

Chain	Residue
C	TYR42
C	PHE43
C	HIS45
C	PHE46
C	HIS58
C	LYS61
C	HIS87
C	ASN97
C	PHE98
C	LEU101
C	VAL132

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HEM D 154

Chain	Residue
D	PHE41
D	PHE42
D	PHE45
D	HIS63
D	LYS66
D	SER70
D	HIS92
D	ASN102
D	LEU141

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM E 155

Chain	Residue
E	TYR42
E	PHE43
E	HIS45
E	PHE46
E	HIS58
E	LYS61
E	HIS87
E	ASN97
E	PHE98
E	LEU101
E	VAL132

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HEM F 156

Chain	Residue
F	PHE41
F	PHE42
F	PHE45
F	HIS63
F	LYS66
F	SER70
F	HIS92
F	ASN102
F	LEU141

---

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM G 157

Chain	Residue
G	TYR42
G	PHE43
G	HIS45
G	PHE46
G	HIS58
G	LYS61
G	HIS87
G	ASN97
G	PHE98
G	LEU101
G	VAL132

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HEM H 158

Chain	Residue
H	PHE41
H	PHE42
H	PHE45
H	HIS63
H	LYS66
H	SER70
H	HIS92
H	ASN102
H	LEU141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1136
Details	Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"description":"distal binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"description":"proximal binding residue"}

Chain

Residue

Details

---