Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0031408 | biological_process | oxylipin biosynthetic process |
| A | 0034440 | biological_process | lipid oxidation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 1990136 | molecular_function | linoleate 9S-lipoxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE A 858 |
| Chain | Residue |
| A | HIS709 |
| A | ASN713 |
| A | ILE857 |
| A | 4HM861 |
| A | HIS518 |
| A | HIS523 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 4HM A 861 |
| Chain | Residue |
| A | GLN514 |
| A | HIS518 |
| A | TRP519 |
| A | HIS523 |
| A | VAL566 |
| A | ILE572 |
| A | ASN713 |
| A | LEU773 |
| A | ILE857 |
| A | FE858 |
| site_id | FE3 |
| Number of Residues | 7 |
| Details | IRON (FE+3) ACTIVE SITE |
| Chain | Residue |
| A | FE858 |
| A | HIS523 |
| A | HIS709 |
| A | ILE857 |
| A | HIS518 |
| A | ASN713 |
| A | 4HM861 |
Functional Information from PROSITE/UniProt
| site_id | PS00081 |
| Number of Residues | 11 |
| Details | LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. VHPIyKLLhPH |
| Chain | Residue | Details |
| A | VAL540-HIS550 | |
| site_id | PS00711 |
| Number of Residues | 15 |
| Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HQlvsHwLNTHAVvE |
| Chain | Residue | Details |
| A | HIS513-GLU527 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS518 | |
| A | HIS523 | |
| A | HIS709 | |
| A | ASN713 | |
| A | ILE857 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1lnh |
| Chain | Residue | Details |
| A | ASN713 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 583 |
| Chain | Residue | Details |
| A | HIS518 | |
| A | HIS523 | |
| A | HIS709 | |
| A | ASN713 | electrostatic stabiliser |
| A | ILE857 | |
